Drug resistance in leprosy: an update following 70 years of chemotherapy

A Aubry, PS Rosa, A Chauffour, ML Fletcher… - Infectious Diseases …, 2022 - Elsevier
Leprosy is one of the oldest infectious diseases, reported for more than 2000 years. Leprosy
elimination goal as a public health problem set by the World Health Organization, aiming for …

[HTML][HTML] Progress and pitfalls in developing agents to treat neurocognitive deficits associated with schizophrenia

T Veselinović, I Neuner - CNS drugs, 2022 - Springer
Cognitive impairments associated with schizophrenia (CIAS) represent a central element of
the symptomatology of this severe mental disorder. CIAS substantially determine the …

[HTML][HTML] Minocycline in major depressive disorder: and overview with considerations on treatment-resistance and comparisons with other psychiatric disorders

MA Nettis - Brain, behavior, & immunity-health, 2021 - Elsevier
Evidence on the link between the immune system and Major Depressive Disorder (MDD)
has led to explore antidepressant properties of anti-inflammatory drugs. Among these …

[HTML][HTML] Niosome as a promising tool for increasing the effectiveness of anti-inflammatory compounds

MS Fadaei, MR Fadaei, AE Kheirieh… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Niosomes are drug delivery systems with widespread applications in pharmaceutical
research and the cosmetic industry. Niosomes are vesicles of one or more bilayers made of …

Efficacy and safety of minocycline quadruple therapy for Helicobacter pylori eradication: a meta‐analysis of RCTs

W Gao, M Zhu, Y Yin, X Zhang, L Wang - Helicobacter, 2023 - Wiley Online Library
Background The effective regimen is lacking in areas with high antibiotic resistance and
tetracycline unavailable. Whether minocycline can replace tetracycline for Helicobacter …

[HTML][HTML] Antifungal Activity of Minocycline and Azoles Against Fluconazole-Resistant Candida Species

J Tan, S Jiang, L Tan, H Shi, L Yang, Y Sun… - Frontiers in …, 2021 - frontiersin.org
Candida species are the most common fungal pathogens to infect humans, and can cause
life-threatening illnesses in individuals with compromised immune systems. Fluconazole …

[HTML][HTML] Molecular and biochemical basis of minocycline-induced hyperpigmentation—the study on normal human melanocytes exposed to UVA and UVB radiation

J Rok, Z Rzepka, J Kowalska, K Banach… - International Journal of …, 2021 - mdpi.com
Minocycline is a drug which induces skin hyperpigmentation. Its frequency reaches up to
50% of treated patients. The adverse effect diminishes the great therapeutic potential of …

[HTML][HTML] Doxycycline post-exposure prophylaxis could theoretically select for resistance to various antimicrobials in 19 pathobionts: an in silico analysis

C Kenyon - International Journal of Infectious Diseases, 2024 - Elsevier
Objectives Doxycycline post exposure prophylaxis (PEP) has been shown to reduce the
incidence of bacterial STIs. However, if there is genetic linkage between resistance to …

Five decades of doxycycline: Does nanotechnology improve its properties?

RC Feitosa, ESA Ishikawa, MFA da Silva… - International journal of …, 2022 - Elsevier
Doxycycline (DX) is a well-established antimicrobial drug that has been used since 1967 to
treat several diseases. This drug has a wide therapeutic range, acting as antibacterial …

Minocycline as a prospective therapeutic agent for cancer and non-cancer diseases: a scoping review

A Rezaei, A Moqadami, M Khalaj-Kondori - … -Schmiedeberg's Archives of …, 2023 - Springer
Minocycline is an FDA-approved secondary-generation tetracycline antibiotic. It is a
synthetic antibiotic having many biological effects, such as antioxidant, anti-inflammatory …