Pulmonary fibrosis is a progressive and ultimately fatal lung disease, exhibiting the
excessive production of extracellular matrix and aberrant activation of fibroblast. While …

Recent breakthroughs in single-cell sequencing, advancements in cellular and tissue
imaging techniques, innovations in cell lineage tracing, and insights into the epigenome …

Cyclic nucleotides are important signaling molecules that play many critical physiological
roles including controlling cell fate and development, regulation of metabolic processes, and …

Nowadays, silica products are widely used in daily life, especially in skin applications, which
inevitably increases the risk of silica exposure in general population. However, inadequate …

Long term exposure to silica particles leads to various diseases, among which silicosis is of
great concern. Silicosis is an interstitial lung disease caused by inhalation of silica particles …

Background Silicosis, characterized by interstitial lung inflammation and fibrosis, poses a
significant health threat. ATII cells play a crucial role in alveolar epithelial repair and …

Esophageal strictures significantly impair patient quality of life and present a therapeutic
challenge, particularly due to the high recurrence post-ESD/EMR. Current treatments …

The widespread manufacture of silica and its extensive use, and potential release of silica
into the environment pose a serious human health hazard. Silicosis, a severe global public …

Silicosis, recognized as a severe global public health issue, is an irreversible pulmonary
fibrosis caused by the long-term inhalation of silica particles. Given the intricate …

Prolonged exposure to free silica leads to the development of silicosis, wherein activated
fibroblasts play a pivotal role in its pathogenesis and progression. Fibroblast Activation …