Human papillomaviruses: diversity, infection and host interactions
AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …
have co-evolved with their host to replicate in specific anatomical niches of the stratified …
Cervical cancer immunotherapy: facts and hopes
It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …
[HTML][HTML] Human papillomavirus E6 and E7: the cervical cancer hallmarks and targets for therapy
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …
The natural history of human papillomavirus infection
S de Sanjose, M Brotons, MA Pavon - Best practice & research Clinical …, 2018 - Elsevier
Human papillomavirus (HPV) is a small double-stranded DNA virus that commonly infects
humans. The oncogenic characteristics of HPV derive from the oncoproteins E6 and E7 that …
humans. The oncogenic characteristics of HPV derive from the oncoproteins E6 and E7 that …
Approved antiviral drugs over the past 50 years
E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
[HTML][HTML] The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review
SV Graham - Clinical science, 2017 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …
[HTML][HTML] Skin cancer: epidemiology, disease burden, pathophysiology, diagnosis, and therapeutic approaches
Skin cancer, including both melanoma and non-melanoma, is the most common type of
malignancy in the Caucasian population. Firstly, we review the evidence for the observed …
malignancy in the Caucasian population. Firstly, we review the evidence for the observed …
[HTML][HTML] Persistent human papillomavirus infection
AN Della Fera, A Warburton, TL Coursey, S Khurana… - Viruses, 2021 - mdpi.com
Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …
cause disease, but rather in the adeptness of the virus to establish long-term persistent …
Human papillomavirus in cervical cancer and oropharyngeal cancer: one cause, two diseases
TA Berman, JT Schiller - Cancer, 2017 - Wiley Online Library
Human papillomavirus (HPV) causes greater than 5% of cancers worldwide, including all
cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs) …
cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs) …