Intense efforts are being undertaken to understand the pathophysiological mechanisms
triggered after brain ischemia and to develop effective pharmacological treatments …

Aim: To investigate the mechanisms underlying the protective effects of sodium tanshinone
IIA sulfonate (STS) in an ischemia-reperfusion (I/R)-induced rat myocardial injury model …

We aimed to investigate the blood brain barrier (BBB) change caused by subarachnoid
hemorrhage (SAH) and to explore the molecular mechanisms of acute brain injury after …

Rhynchophylline (Rhy) is an alkaloid isolated from Uncaria which has long been
recommended for the treatment of central nervous diseases. In our study, the …

The hypoxia-inducible factor (HIF) family of transcription factors is responsible for
coordinating the cellular response to low oxygen levels in animals. By regulating the …

Glaucoma is a complex neurodegenerative disease characterized by optic nerve damage
and apoptotic retinal ganglion cell (RGC) death, and is the leading cause of irreversible …

Objective Ischemic stroke is known as a neurodegenerative disorder, which induces long‐
period tissue damage. Chemokine (C–X–C motif) ligand 8 (CXCL8) is involved in acute …

Neuroimmune processes contribute to hypoxic–ischemic damage in the immature brain and
may play a role in the progression of particular variants of neonatal encephalopathy. The …

Abstract Background The Blood Brain Barrier (BBB) maintains the homeostasis of central
nervous system by preventing the free passage of macromolecules from the systemic …

Objective The purpose of the present study is to investigate whether angiopoietin-like 4
(ANGPTL4) can promote angiogenesis and neurogenesis following stroke, as well as to …