Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

In the oncology community, opioids recently have become the cornerstone of cancer pain
management. This has led to a rapid increase in opioid prescribing in an effort to address …

Physicians can encounter problems in prescribing opioids for some patients with chronic
pain such as multiple unsanctioned dose escalations, episodes of lost or stolen …

In this paper we estimate the risk of becoming cannabis dependent within 24 months after
first use of cannabis and examine subgroup variation in this risk. The study estimates are …

Using historical research that draws on new primary sources, I review the causes and
course of the first, mainly iatrogenic amphetamine epidemic in the United States from the …

OBJECTIVES: This study examined recent trends in initiation of psychoactive drug use.
METHODS: Data from the 1991 through 1993 National Household Surveys on Drug Abuse …

PURPOSE: The full text of this article is available on JAH Online at. To examine the
association between employment status and substance use among students aged 12 to 17 …

The bully pulpit is one of the modern president's most powerful tools—and one of the most
elusive to measure. Presidential Rhetoric and the Public Agenda uses the war on drugs as a …

We set up a time-continuous version of the first-order difference equation model of cocaine
use introduced by Everingham and Rydell [SS Everingham, CP Rydell, Modeling the …

The FDA's 2012 risk evaluation and mitigation strategy is a major step toward systematically
reducing the inherent risks of chronic opioid therapy for pain, but does not distinguish …