Extensive research in the past decade has significantly broadened our view about the role
actin plays in the life of the cell and added novel aspects to actin research. One of these new …

Recent years have provided considerable insights into the dynamic nature of the cell
nucleus, which is constantly reorganizing its genome, controlling its size and shape, as well …

Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that
nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. NM1 directly …

Highlights•Nuclear actin exists in both monomeric and polymeric forms.•Actin monomers
have been mainly linked to regulation of gene expression.•Polymerized nuclear actin …

Background Nuclear lamins are type V intermediate filament proteins that maintain nuclear
structure and function. Furthermore, Emerin-an interactor of Lamin A/C, facilitates crosstalk …

Troponin is a heterotrimeric Ca 2+-binding protein that has a well-established role in
regulating striated muscle contraction. However, mounting evidence points to novel cellular …

During differentiation and development, cell fate and identity are established by waves of
genetic reprogramming. Although the mechanisms are largely unknown, during these …

During DNA damage response (DDR), certain gene rich chromosome territories (CTs)
relocate to newer positions within interphase nuclei and revert to their native locations …

This paper describes a novel type of nuclear structure–nuclear lipid islets (NLIs). They are of
40–100 nm with a lipidic interior, and phosphatidylinositol 4, 5-bisphosphate [PtdIns (4, 5) …

Although best known from its functions in the cytoplasm, actin also localizes to the cell
nucleus, where it has been linked to many essential functions from regulation of gene …