Aims Cigarette smoke often induces pulmonary and systemic inflammation. In animal
models, mesenchymal stem cells (MSC) tend to ameliorate these effects. We aimed to …

Since the discovery of Cardiac progenitor cells (CPCs) in the early 1990s, they have been
studied extensively in different models and clinical trials to treat various heart diseases …

Mesenchymal stem cells (MSCs) are a rich source of bioactive molecules, which they
secrete as a part of their paracrine activity. Additionally, given their immunomodulatory and …

Mesenchymal stem cells are considered the key cells in tissue regeneration after damage.
MSCs play a fundamental role in cancer since they can be recruited to induce tumor growth …

The epicardium is an essential actor during heart development since its active participation
in cardiac cell differentiation via cellular contact and paracrine activity. These cellular and …

Stem cells are clonogenic cells capable of self-renewal and multi-lineage differentiation.
Since the first isolation of dental pulp stem cells (DPSCs) in the early 2000s, stem cell …

Cell-and gene-based therapies form one of the pillars of regenerative medicine. This
chapter reviews the recent progress in applying advanced therapy medicinal products …

Myocarditis is an inflammatory disease of the heart. Immune cells of innate immunity
(dendritic cells, macrophages, neutrophils, natural killer, and natural killer T cells) and …

Heart failure (HF) remains the most prominent cause of cardiovascular morbidity and
mortality. The underlying molecular mechanisms of the natural evolution of HF affect cardiac …

Cellular therapy of the corneal stroma, either with ocular or extraocular stem cells, has
gained significant interest over the last decade. Multiple studies showed benefits such as …