The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Pseudomonas genomes: diverse and adaptable

MW Silby, C Winstanley, SAC Godfrey… - FEMS microbiology …, 2011 - academic.oup.com
Members of the genus Pseudomonas inhabit a wide variety of environments, which is
reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating …

A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria

RD Hood, P Singh, FS Hsu, T Güvener, MA Carl… - Cell host & …, 2010 - cell.com
The functional spectrum of a secretion system is defined by its substrates. Here we analyzed
the secretomes of Pseudomonas aeruginosa mutants altered in regulation of the Hcp …

Regulation of bacterial virulence by Csr (Rsm) systems

CA Vakulskas, AH Potts, P Babitzke… - Microbiology and …, 2015 - Am Soc Microbiol
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein Secretion Apparatus

JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou… - Science, 2006 - science.org
Bacterial pathogens frequently use protein secretion to mediate interactions with their hosts.
Here we found that a virulence locus (HSI-I) of Pseudomonas aeruginosa encodes a protein …

Type VI secretion and anti-host effectors

A Hachani, TE Wood, A Filloux - Current opinion in microbiology, 2016 - Elsevier
Highlights•T6SS is a secretion system involved in the virulence of bacterial pathogens.•This
versatile weapon can target both prokaryotic and eukaryotic cells.•The T6SS tail/spike …

Iron and Pseudomonas aeruginosa biofilm formation

E Banin, ML Vasil… - Proceedings of the …, 2005 - National Acad Sciences
Iron serves as a signal in Pseudomonas aeruginosa biofilm development. We examined the
influence of mutations in known and putative iron acquisition-signaling genes on biofilm …

Two-component systems required for virulence in Pseudomonas aeruginosa

VI Francis, EC Stevenson, SL Porter - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad
range of hosts, in addition to thriving in a broad range of environmental conditions outside of …

Protein secretion systems in Pseudomonas aeruginosa: a wealth of pathogenic weapons

S Bleves, V Viarre, R Salacha, GPF Michel… - International Journal of …, 2010 - Elsevier
Pathogenic microorganisms have to face hostile environments while colonizing and
infecting their hosts. Unfortunately, they can cope with it and have evolved a number of …

The Pseudomonas aeruginosa sensor RetS switches Type III and Type VI secretion via c‐di‐GMP signalling

JA Moscoso, H Mikkelsen, S Heeb… - Environmental …, 2011 - Wiley Online Library
Acute bacterial infections are associated with motility and cytotoxicity via the type III
secretion system (T3SS), while chronic infections are linked to biofilm formation and reduced …