The weight of IgA anti-β2glycoprotein I in the antiphospholipid syndrome pathogenesis: closing the gap of seronegative antiphospholipid syndrome

O Cabrera-Marante, E Rodríguez de Frías… - International Journal of …, 2020 - mdpi.com
The specific value of IgA Anti-β2glycoprotein I antibodies (aB2GP1) in the diagnosis and
management of antiphospholipid syndrome (APS) is still controversial and a matter of active …

Global antiphospholipid syndrome score and anti-ß2-glycoprotein I domain I for thrombotic risk stratification in antiphospholipid syndrome: a four-year prospective …

IS Nascimento, M Radin, APR Gândara, S Sciascia… - Lupus, 2020 - journals.sagepub.com
Objective This study aimed to assess prospectively the role of anti-ß2-glycoprotein I domain I
antibody (aß2GPI-DI) and the Global Antiphospholipid Syndrome Score (GAPSS) in …

Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers

D Roggenbuck, MO Borghi, V Somma, T Büttner… - Arthritis research & …, 2016 - Springer
Background Antiphospholipid antibodies (aPL) can be detected in asymptomatic carriers
and infectious patients. The aim was to investigate whether a novel line immunoassay (LIA) …

Laboratory evaluation of antiphospholipid syndrome: an update on autoantibody testing

AE Tebo - Clinics in Laboratory Medicine, 2019 - labmed.theclinics.com
Antiphospholipid (aPL) syndrome (APS) is an autoimmune disorder characterized by
thrombosis and/or certain pregnancy-related complications in association with persistence …

Cerebral microhemorrhage and purpuric rash in COVID-19: the case for a secondary microangiopathy

A Shoskes, I Migdady, A Fernandez, P Ruggieri… - Journal of Stroke and …, 2020 - Elsevier
Introduction Since the emergence of Coronavirus Disease 19 (COVID-19) pandemic,
multiple neurologic complications in infected patients have been reported. Despite these …

[HTML][HTML] A multicenter study to assess the reproducibility of antiphospholipid antibody results produced by an automated system

KM Devreese, A Poncet, E Lindhoff‐Last… - Journal of Thrombosis …, 2017 - Elsevier
Essentials• Inter‐lab variation studies for antiphospholipid antibodies (aPL) with the same
assay are lacking.• We carried out an assessment of repeatability and reproducibility of an …

Immunoglobulin A isotype of antiphospholipid antibodies does not provide added value for the diagnosis of antiphospholipid syndrome in a Chinese population

C Hu, X Li, J Zhao, Q Wang, M Li, X Tian… - Frontiers in …, 2020 - frontiersin.org
Objective Antiphospholipid syndrome (APS) is characterized by the presence of anti-
phospholipid (aPL) antibodies. However, the relationship between the immunoglobulin (Ig) …

[HTML][HTML] Clinical characteristics and laboratory findings of 252 Chinese patients with anti-phospholipid syndrome: comparison with Euro-Phospholipid cohort

H Shi, J Teng, Y Sun, X Wu, Q Hu, H Liu, X Cheng… - Clinical …, 2017 - Springer
This study aims to characterize the Chinese Han patients with anti-phospholipid syndrome
(APS) and compare the data with those of the Euro-Phospholipid cohort. We conducted a …

Evaluation of the diagnostic potential of antibodies to beta2-glycoprotein 1 domain 1 in Chinese patients with antiphospholipid syndrome

S Zhang, Z Wu, S Chen, J Li, X Wen, L Li, W Zhang… - Scientific reports, 2016 - nature.com
In this study, we evaluated the clinical performance of anti-β2-glycoprotein 1 domain 1
antibodies (aβ2GP1-D1) in the diagnosis of antiphospholipid syndrome (APS). Sera from …

[HTML][HTML] Significance of fully automated tests for the diagnosis of antiphospholipid syndrome

K Oku, O Amengual, M Kato, T Bohgaki, T Horita… - Thrombosis …, 2016 - Elsevier
Antiphospholipid antibodies (aPLs) can vary both immunologically and functionally, thus it is
important to effectively and correctly identify their presence when diagnosing …