The evolving concept of poor-prognosis for women undertaking IVF and the notion of growth hormone as an adjuvant; a single-center viewpoint

JL Yovich, Y Ye, SLP Regan, KN Keane - Frontiers in Endocrinology, 2019 - frontiersin.org
IVF is currently regarded as a successful new technology with the number of IVF children
currently well over 8 million worldwide. This has been achieved by an explosive plethora of …

Effects of growth hormone supplementation on poor ovarian responders in assisted reproductive technology: a systematic review and meta-analysis

FT Liu, KL Hu, R Li - Reproductive Sciences, 2021 - Springer
To investigate whether additional growth hormone (GH) treatment can improve pregnancy
outcomes in poor ovarian responders (POR), this systematic review and meta-analysis is …

Growth hormone supplementation may not improve live birth rate in poor responders

J Zhu, Y Wang, L Chen, P Liu, R Li… - Frontiers in endocrinology, 2020 - frontiersin.org
Backgrounds: Growth hormone (GH) was used for many years to increase ovarian response
in poor ovarian responders (PORs). Although meta-analysis suggested that GH therapy …

Growth hormone for in vitro fertilisation (IVF)

A Sood, G Mohiyiddeen, G Ahmad… - Cochrane Database …, 2021 - cochranelibrary.com
Background In an effort to improve outcomes of in vitro fertilisation (IVF) cycles, the use of
growth hormone (GH) has been considered as adjuvant treatment in ovarian stimulation …

DHEA supplementation confers no additional benefit to that of growth hormone on pregnancy and live birth rates in IVF patients categorized as poor prognosis

KN Keane, PM Hinchliffe, PK Rowlands… - Frontiers in …, 2018 - frontiersin.org
Background In vitro fertilization (IVF) patients receive various adjuvant therapies to enhance
success rates, but the true benefit is actively debated. Growth hormone (GH) and …

Comparative efficacy of different growth hormone supplementation protocols in improving clinical outcomes in women with poor ovarian response undergoing …

Z Xu, W Tong, Z Yang, H Zhang, X Chen - Scientific Reports, 2024 - nature.com
Growth hormone (GH) has a long-standing history of use as an adjunctive therapy in the
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …

Low dose growth hormone adjuvant treatment with ultra-long ovarian stimulation protocol in poor responders showed non-inferior pregnancy outcome compared with …

YX Lee, MS Shen, CR Tzeng - Frontiers in Endocrinology, 2019 - frontiersin.org
Background: Growth hormone (GH) has long been used as adjuvant treatment in ovarian
stimulation for in vitro fertilization (IVF), especially in poor responder (PR) patients. However …

[HTML][HTML] Efficacy of growth hormone supplementation with ultrashort GnRH antagonist in IVF/ICSI for poor responders; randomized controlled trial

EH Mohammad, AG Abou El Serour… - Taiwanese Journal of …, 2021 - Elsevier
Objectives To compare the ICSI-ET outcomes in poor responders who underwent ovarian
stimulation by the ultrashort GnRH antagonist protocol with or without adjuvant GH injection …

[HTML][HTML] Live birth outcomes of vitrified embryos generated under growth hormone stimulation are improved for women categorized as poor-prognosis

KN Keane, Y Ye, PM Hinchliffe… - Clinical and …, 2019 - ncbi.nlm.nih.gov
Objective To determine the clinical pregnancy (CP) and live birth (LB) rates arising from
frozen embryo transfers (FETs) that had been generated under the influence of in vitro …

Growth hormone supplementation ameliorates blastocyst euploidy rates and improves pregnancy outcomes in women undergoing preimplantation genetic testing for …

Q Guo, P Liu, W Zhou, M Xia, J Li, J Lu, JL Ma… - Frontiers in …, 2023 - frontiersin.org
Background Growth hormone (GH) supplementation has been shown to improve oocyte
quality and live birth, but few studies have examined whether GH can reduce embryonic …