Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review
A biomarker describes a measurable indicator of a patient's clinical condition that can be
measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis …
measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis …
Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019—results from a systematic review and meta-analysis
M Bauer, H Gerlach, T Vogelmann, F Preissing… - Critical Care, 2020 - Springer
Background Sepsis and septic shock remain drivers for mortality in critically ill patients. The
heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality …
heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality …
The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation …
Background There is a lack of validated tools to assess potential disease progression and
hospitalisation decisions in patients presenting to the emergency department (ED) with a …
hospitalisation decisions in patients presenting to the emergency department (ED) with a …
Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: An observational prospective study
G Montrucchio, G Sales, F Rumbolo, F Palmesino… - PLoS …, 2021 - journals.plos.org
Objective To test the effectiveness of mid-regional pro-adrenomedullin (MR-proADM) in
comparison to C-reactive protein (CRP), procalcitonin (PCT), D-dimer, lactate …
comparison to C-reactive protein (CRP), procalcitonin (PCT), D-dimer, lactate …
MR-proADM as prognostic factor of outcome in COVID-19 patients
Abstract Mid Regional pro-ADM (MR-proADM) is a promising novel biomarker in the
evaluation of deteriorating patients and an emergent prognosis factor in patients with sepsis …
evaluation of deteriorating patients and an emergent prognosis factor in patients with sepsis …
Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases
T Kita, K Kitamura - Hypertension Research, 2022 - nature.com
Adrenomedullin (AM) is a vasodilative peptide with various physiological functions,
including the maintenance of vascular tone and endothelial barrier function. AM levels are …
including the maintenance of vascular tone and endothelial barrier function. AM levels are …
Mid-regional pro-adrenomedullin (MR-proADM) as a biomarker for sepsis and septic shock: narrative review
Early identification and diagnosis of sepsis and septic shock is vitally important; despite
appropriate management, mortality and morbidity rates remain high. For this reason, many …
appropriate management, mortality and morbidity rates remain high. For this reason, many …
Basal procalcitonin, C-reactive protein, interleukin-6, and presepsin for prediction of mortality in critically ill septic patients: a systematic review and meta-analysis
Background Numerous biomarkers have been proposed for diagnosis, therapeutic, and
prognosis in sepsis. Previous evaluations of the value of biomarkers for predicting mortality …
prognosis in sepsis. Previous evaluations of the value of biomarkers for predicting mortality …
[HTML][HTML] The vasoactive peptide MR-pro-adrenomedullin in COVID-19 patients: an observational study
C Gregoriano, D Koch, A Kutz, S Haubitz… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Midregional pro-adrenomedullin (MR-proADM) is a vasoactive peptide with key
roles in reducing vascular hyperpermeability and thereby improving endothelial stability …
roles in reducing vascular hyperpermeability and thereby improving endothelial stability …
High value of mid‐regional proadrenomedullin in COVID‐19: A marker of widespread endothelial damage, disease severity, and mortality
S Spoto, FE Agrò, F Sambuco… - Journal of Medical …, 2021 - Wiley Online Library
The widespread endothelial damage due to severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) may lead to a disruption of the adrenomedullin (ADM) system responsible …
2 (SARS‐CoV‐2) may lead to a disruption of the adrenomedullin (ADM) system responsible …