Highlights•Coaxial electrospinning generates fibers with core–shell structure mimicking the
extracellular matrix.•Core–shell fibers are controlled delivery platforms of biocompounds for …

The biofabrication of biomimetic scaffolds for tissue engineering applications is a field in
continuous expansion. Of particular interest, nanofibrous scaffolds can mimic the …

Electrospun nanofibers mimic the native extracellular matrix of bone and have generated
considerable interest in bone tissue regeneration. The aim of this study was to fabricate …

In this study, a three-dimensional tablet-like porous scaffold, comprising core-shell fibers to
host proteins inside the core, was developed. The fabrication method involved the novel …

The surgical connection of blood vessels, anastomosis, is a critical procedure in many
reparative, transplantation, and reconstructive surgical procedures. However, effective …

The poor patency rate following small-diameter vascular grafting remains a major hurdle for
the widespread clinical application of artificial blood vessels to date. Our previous studies …

Studies have shown that salvianolic acid B (SAB), which is derived from Chinese salvia
(Salvia miltiorrhiza), a plant used in traditional Chinese medicine, can promote the …

The physiological and pathological complexity of the wound healing process makes it more
challenging to design an ideal tissue regeneration scaffold. Precise scaffolding with high …

The development of therapeutic approaches for spinal cord injury (SCI) is still a challenging
goal to achieve. The pathophysiological features of chronic SCI are glial scar and cavity …

Small diameter vascular grafts possessing desirable biocompatibility and suitable
mechanical properties have become an urgent clinic demand. Herein, heparin loaded …