Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …
The chronic and evolving neurological consequences of traumatic brain injury
Traumatic brain injury (TBI) can have lifelong and dynamic effects on health and wellbeing.
Research on the long-term consequences emphasises that, for many patients, TBI should be …
Research on the long-term consequences emphasises that, for many patients, TBI should be …
Severe traumatic brain injury: targeted management in the intensive care unit
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …
combined medical–surgical approach. Treatment aims to prevent additional brain damage …
Accuracy of EEG biomarkers in the detection of clinical outcome in disorders of consciousness after severe acquired brain injury: preliminary results of a pilot study …
Accurate outcome detection in neuro-rehabilitative settings is crucial for appropriate long-
term rehabilitative decisions in patients with disorders of consciousness (DoC). EEG …
term rehabilitative decisions in patients with disorders of consciousness (DoC). EEG …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
[HTML][HTML] Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction
Traumatic brain injury (TBI) leads to lasting brain dysfunction with chronic
neuroinflammation typified by nucleotide-binding domain leucine-rich repeat and pyrin …
neuroinflammation typified by nucleotide-binding domain leucine-rich repeat and pyrin …
Biomaterials and cells for neural tissue engineering: Current choices
P Sensharma, G Madhumathi, RD Jayant… - Materials Science and …, 2017 - Elsevier
The treatment of nerve injuries has taken a new dimension with the development of tissue
engineering techniques. Prior to tissue engineering, suturing and surgery were the only …
engineering techniques. Prior to tissue engineering, suturing and surgery were the only …
Extracellular vesicles derived from neural stem cells, astrocytes, and microglia as therapeutics for easing TBI-induced brain dysfunction
C Hering, AK Shetty - Stem cells translational medicine, 2023 - academic.oup.com
Extracellular vesicles (EVs) derived from neural stem cells (NSC-EVs), astrocytes (ADEVs),
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …