[HTML][HTML] Non-genomic effects of estrogen on cell homeostasis and remodeling with special focus on cardiac ischemia/reperfusion injury

R Puglisi, G Mattia, A Carè, G Marano… - Frontiers in …, 2019 - frontiersin.org
This review takes into consideration the main mechanisms involved in cellular remodeling
following an ischemic injury, with special focus on the possible role played by non-genomic …

The protective effects of 17-β estradiol and SIRT1 against cardiac hypertrophy: A review

Z Hajializadeh, M Khaksari - Heart Failure Reviews, 2022 - Springer
One of the major causes of morbidity and mortality worldwide is cardiac hypertrophy (CH),
which leads to heart failure. Sex differences in CH can be caused by sex hormones or their …

Resveratrol attenuates myocardial ischemia/reperfusion injury through up-regulation of vascular endothelial growth factor B

L Yang, Y Zhang, M Zhu, Q Zhang, X Wang… - Free Radical Biology …, 2016 - Elsevier
The objective was to examine the protective effect of resveratrol (RSV) on myocardial
ischemia/reperfusion (IR) injury and whether the mechanism was related to vascular …

[HTML][HTML] Sex differences in cardiovascular diseases: a matter of estrogens, ceramides, and sphingosine 1-phosphate

B Arosio, G Corbi, S Davinelli, V Giordano… - International Journal of …, 2022 - mdpi.com
The medical community recognizes sex-related differences in pathophysiology and
cardiovascular disease outcomes (CVD), culminating with heart failure. In general, pre …

GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway

X Wang, L Lu, Y Tan, L Jiang, M Zhao, E Gao, S Yu… - Life sciences, 2019 - Elsevier
Aims Estrogen plays an important role in cardioprotection. Animal experiments showed that
the G-protein coupled estrogen receptor 30 (GPR30) specific agonist G1 could reduce post …

Molecular pathways of oestrogen receptors and β‐adrenergic receptors in cardiac cells: Recognition of their similarities, interactions and therapeutic value

JO Machuki, HY Zhang, SE Harding, H Sun - Acta Physiologica, 2018 - Wiley Online Library
Oestrogen receptors (ERs) and β‐adrenergic receptors (βARs) play important roles in the
cardiovascular system. Moreover, these receptors are expressed in cardiac myocytes and …

[HTML][HTML] Notch1 mediates preconditioning protection induced by GPER in normotensive and hypertensive female rat hearts

C Rocca, S Femminò, G Aquila, MC Granieri… - Frontiers in …, 2018 - frontiersin.org
G protein-coupled estrogen receptor (GPER) is an estrogen receptor expressed in the
cardiovascular system. G1, a selective GPER ligand, exerts cardiovascular effects through …

[HTML][HTML] Role of β-adrenergic receptors and estrogen in cardiac repair after myocardial infarction: An overview

P Matarrese, S Maccari, R Vona… - International Journal of …, 2021 - mdpi.com
Acute myocardial infarction (MI) is associated with an intense inflammatory response that is
critical for cardiac repair but is also involved in the pathogenesis of adverse cardiac …

[HTML][HTML] Age-associated changes in estrogen receptor ratios correlate with increased female susceptibility to coxsackievirus B3-induced myocarditis

A Koenig, I Buskiewicz, SA Huber - Frontiers in immunology, 2017 - frontiersin.org
Sexual bias is a hallmark in various diseases. This review evaluates sexual dimorphism in
clinical and experimental coxsackievirus B3 (CVB3) myocarditis, and how sex bias in the …

[HTML][HTML] GPER agonist G1 suppresses neuronal apoptosis mediated by endoplasmic reticulum stress after cerebral ischemia/reperfusion injury

ZW Han, YC Chang, Y Zhou, H Zhang… - Neural regeneration …, 2019 - journals.lww.com
Studies have confirmed a strong association between activation of the endoplasmic
reticulum stress pathway and cerebral ischemia/reperfusion (I/R) injury. In this study, three …