Acute myocardial infarction (MI) is associated with an intense inflammatory response that is
critical for cardiac repair but is also involved in the pathogenesis of adverse cardiac …

Postmenopausal depression has been shown to be related to the reduction of ovarian
hormones produced as a woman transitions from a menopausal to a post-menopausal …

Compared with age-matched men, premenopausal women are largely protected from
coronary artery disease, a difference that is lost after menopause. The effects of oestrogens …

The mechanisms underlying hypertension are multifaceted and incompletely understood.
New evidence suggests that G protein-coupled estrogen receptor 1 (GPER1) mediates …

Premenopausal women have a reduced risk for cardiovascular disease. Estrogen deficiency
augments cardiac inflammation and oxidative stress and, thereby, aggravates myocardial …

Several lines of evidence suggest that exposures to Endocrine Disrupting Chemicals
(EDCs) such as pesticides increase the risks of neuropsychiatric disorders. Despite …

G protein-coupled receptors (GPCRs) are cell surface proteins mainly involved in signal
transmission; however, they play a role also in several pathophysiological conditions …

Cardiovascular (CV) and renal diseases are increasingly prevalent in the United States and
globally. CV-related mortality is the leading cause of death in the United States, while renal …

Sex differences are consistently identified in determining the prevalence, manifestation, and
response to therapies in several systemic disorders, including those affecting the …

As an agonist of the classical nuclear receptors, estrogen receptor‐α and‐β (NR3A1/2),
estrogen has been assumed to inhibit the development of cardiovascular disease in …