Sex difference in GPER expression does not change vascular relaxation or reactive oxygen species generation in rat mesenteric resistance arteries

P Peixoto, JF da Silva, RD Aires, ED Costa, VS Lemos… - Life sciences, 2018 - Elsevier
Aim An imbalance between antioxidant and pro-oxidant factors, with a predominance of the
latter, characterises oxidative stress and is indicative of a loss of vascular function. The …

Estrogenic impact on cardiac ischemic/reperfusion injury

S Sivasinprasasn, K Shinlapawittayatorn… - Journal of …, 2016 - Springer
The increase in cardiovascular disease and metabolic syndrome incidence following the
onset of menopause has highlighted the role of estrogen as a cardiometabolic protective …

DPP-4 inhibitor and estrogen share similar efficacy against cardiac ischemic-reperfusion injury in obese-insulin resistant and estrogen-deprived female rats

S Sivasinprasasn, P Tanajak, W Pongkan… - Scientific reports, 2017 - nature.com
Estrogen deprivation aggravates cardiac injury after myocardial ischemia and reperfusion
(I/R) injury. Although either estrogen or the dipeptidyl peptidase-4 (DPP-4) inhibitor …

G protein-coupled receptor 30 activation protects hepatic ischemia-reperfusion injury of liver tissue through inhibiting NLRP3 in the rat model

Y Qin, CJ Wang, SQ Xu, CJ Wu, S Wang… - Journal of …, 2021 - Taylor & Francis
One of the most prominent characteristics of hepatic ischemia-reperfusion injury (HI/R) is an
intense inflammatory reaction, which plays a key role in inflammatory injury induced by …

[HTML][HTML] G-protein coupled estrogen receptor activation protects the viability of hyperoxia-treated primary murine retinal microglia by reducing ER stress

R Li, Y Wang, P Chen, J Meng, H Zhang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
In this study, we investigated the effects of G-protein coupled estrogen receptor (GPER)
activation in the early phase of retinopathy of prematurity (ROP) and its association with …

The activation of the G protein-coupled estrogen receptor (GPER) prevents and regresses cardiac hypertrophy

RA Di Mattia, JIE Mariángelo, PG Blanco, CJ De Giusti… - Life sciences, 2020 - Elsevier
Ventricular hypertrophy is a risk factors for arrhythmias, ischemia and sudden death. It
involves cellular modifications leading to a pathological remodeling and is associated with …

Mechanisms of sex disparities in cardiovascular function and remodeling

S Chaudhari, SC Cushen, O Osikoya… - Comprehensive …, 2011 - Wiley Online Library
Epidemiological studies demonstrate disparities between men and women in cardiovascular
disease prevalence, clinical symptoms, treatments, and outcomes. Enrollment of women in …

Expression and regulation of glucocorticoid-induced leucine zipper in the developing anterior pituitary gland

LE Ellestad, SA Malkiewicz, HD Guthrie… - Journal of …, 2009 - jme.bioscientifica.com
The role of the adipocyte-derived factor visfatin in metabolism remains controversial,
although some pancreatic β-cell-specific effects have been reported. This study investigated …

[HTML][HTML] The importance of G-protein coupled estrogen receptor in patients with fibromyalgia

K Tuba, B Koçyiğit, M Seyithanoğlu… - Archives of …, 2019 - ncbi.nlm.nih.gov
The Importance of G-protein Coupled Estrogen Receptor in Patients With Fibromyalgia - PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Does G Protein-Coupled Estrogen Receptor 1 Contribute to Cisplatin-Induced Acute Kidney Injury in Male Mice?

EY Gohar, RN Almutlaq, C Fan, RS Balkawade… - International Journal of …, 2022 - mdpi.com
Nephrotoxicity is the dose-limiting side-effect of the chemotherapeutic agent cisplatin (Cp).
Recent evidence points to renal protective actions of G protein-coupled estrogen receptor 1 …