Estrogen and DPP-4 inhibitor share similar efficacy in reducing brain pathology caused by cardiac ischemia-reperfusion injury in both lean and obese estrogen …

W Pratchayasakul, S Sivasinprasasn… - Menopause, 2017 - journals.lww.com
Objective: Cardiac ischemia-reperfusion injury (I/R) caused an oxidative burst, increased
beta-amyloid production, and decreased dendritic spine density in the brain. However, the …

The role of GPER signaling in carcinogenesis: a focus on prostate Cancer

MI Figueira, HJ Cardoso, S Socorro - Recent Trends in Cancer Biology …, 2018 - Springer
The G protein-coupled estrogen receptor, GPER, also known as GPR30, belongs to the
seven transmembrane receptor superfamily and is involved in the rapid non-genomic …

Restoration of adiponectin-Connexin43 signaling mitigates myocardial inflammation and dysfunction in diabetic female rats

KE Leffler, AA Abdel-Rahman - Journal of cardiovascular …, 2020 - journals.lww.com
Abstract ur preclinical findings replicated women's hypersensitivity to type-2 diabetes
mellitus (T2DM)-evoked cardiac dysfunction along with demonstrating estrogen (E 2) …

Estrogen: Impact on cardiomyocytes and the heart

JK Kim - Principles of gender-specific medicine, 2017 - Elsevier
The mechanisms behind gender differences in the experience of cardiovascular diseases
remain obscure. Women are less affected by ischemic heart disease until menopause, after …

[PDF][PDF] 雌激素受体GPER 通过抑制内质网应激减轻脑缺血再灌注损伤

韩子伟, 朱立仓, 常越辰, 周颖, 宗家安, 马克涛… - 生理学报, 2019 - researchgate.net
本文旨在研究G 蛋白耦联雌激素受体(G protein-coupled estrogen receptor, GPER)
是否通过作用于内质网应激(endoplasmic reticulum stress, ERS) 减轻脑缺血再灌注损伤 …

GPER 激动剂G1 可抑制脑缺血再灌注后内质网应激引起的细胞凋亡

ZW Han, YC Chang, Y Zhou, H Zhang… - 中国神经再生研究 …, 2019 - sjzsyj.com.cn
已有研究显示, 内质网应激途径的激活与脑缺血再灌注损伤密切相关. 因此实验选取内质网应激
介导的细胞凋亡途径中的关键蛋白GRP78, Caspase-12 及CHOP 来研究内质网应激在G …

[引用][C] G 蛋白偶联雌激素受体在心血管疾病中的作用

张文, 付炜, 张海波 - 国际心血管病杂志, 2016

Cardiomyocyte Responses to Hormones

CC Kartha, CC Kartha - Cardiomyocytes in Health and Disease, 2021 - Springer
Several hormones and their receptors have a critical role in the homeostasis of
cardiomyocytes. They also modulate pathophysiological alterations in the cells and are …

[图书][B] The Research Advances in G-Protein-Coupled Estrogen Receptor

HB Zhang, Y Wang, B Wang - 2022 - intechopen.com
Estrogen binds to the typical estrogen receptor (ER) ERα or ERβ and is translocated to the
nucleus, where it binds directly to the estrogen response element of the target gene to …

[PDF][PDF] DPP-4 Inhibitor and Estrogen Share Similar Efficacy Against Cardiac Ischemic-Reperfusion Injury in Obese-Insulin Resistant and Estrogen-Deprived Female …

W Pratchayasakul, SC Chattipakorn, N Chattipakorn - academia.edu
Results Efficacy of estrogen and vildagliptin on metabolic status. The estrogen-deprived rats
demonstrated several features of obese-insulin resistance as indicated by significantly …