Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or
subcutaneous administration. The low molecular weight, high potency and lipid solubility of …

Transdermal delivery allows continuous systemic application of opioids through the intact
skin. This review analyses the pharmacokinetic properties of transdermal opioid …

▪ Abstract Summary of consensus: 1. The use of opioids in cancer pain: The criteria for
selecting analgesics for pain treatment in the elderly include, but are not limited to, overall …

The transfollicular administration of pharmacologically active molecules is of current
therapeutic interest, mainly with regard to delivery to specific sites of the hair follicle (HF) and …

The prevalence of fentanyl abuse raises global public health concerns with an
unprecedented surge in overdose deaths. Rapid identification and quantification of fentanyl …

Objective: To discuss the historical basis and limitations of opioid conversion tables, review
the relevant literature, and establish an evidence-based equianalgesic dose ratio (EDR) …

Direct conversion from oral morphine to transdermal fentanyl with a ratio of oral
morphine/transdermal fentanyl (100: 1 mg) daily was examined in patients with cancer pain …

Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused
by malignancy and non-malignant conditions when administered according to the …

Pancreatic cancer has a very poor prognosis and is often associated with severe pain. A
variety of pain syndromes and pain pathophysiologies can be identified. Information about …

Eleven patients with cancer pain in a palliative care and chronic pain service required
cessation of morphine due to unacceptable opioid side effects. In this retrospective study …