Terahertz time-domain spectroscopy

M Koch, DM Mittleman, J Ornik… - Nature Reviews Methods …, 2023 - nature.com
The terahertz band of the electromagnetic spectrum was the least explored region of the
spectrum prior to the introduction of the technique known as time-domain spectroscopy …

[HTML][HTML] Terahertz (THz) biophotonics technology: Instrumentation, techniques, and biomedical applications

X Chen, H Lindley-Hatcher, RI Stantchev… - Chemical Physics …, 2022 - pubs.aip.org
Terahertz (THz) technology has experienced rapid development in the past two decades.
Growing numbers of interdisciplinary applications are emerging, including materials …

Perspective on terahertz applications in bioscience and biotechnology

AG Markelz, DM Mittleman - Acs Photonics, 2022 - ACS Publications
Within the field of terahertz science and technology, one of the most active areas of current
research focuses on the intersection of terahertz measurements and methods with the world …

[HTML][HTML] Supervised machine learning for automatic classification of in vivo scald and contact burn injuries using the terahertz Portable Handheld Spectral Reflection …

ME Khani, ZB Harris, OB Osman, JW Zhou, A Chen… - Scientific Reports, 2022 - nature.com
We present an automatic classification strategy for early and accurate assessment of burn
injuries using terahertz (THz) time-domain spectroscopic imaging. Burn injuries of different …

In vivo assessment and monitoring of burn wounds using a handheld terahertz hyperspectral scanner

OB Osman, ZB Harris, JW Zhou… - Advanced photonics …, 2022 - Wiley Online Library
The accuracy of clinical assessment techniques in diagnosing partial‐thickness burn injuries
has remained as low as 50–76%. Depending on the burn depth and environmental factors …

Triage of in vivo burn injuries and prediction of wound healing outcome using neural networks and modeling of the terahertz permittivity based on the double Debye …

ME Khani, ZB Harris, OB Osman, AJ Singer… - Biomedical Optics …, 2023 - opg.optica.org
The initial assessment of the depth of a burn injury during triage forms the basis for
determination of the course of the clinical treatment plan. However, severe skin burns are …

Accurate and early prediction of the wound healing outcome of burn injuries using the wavelet Shannon entropy of terahertz time-domain waveforms

ME Khani, OB Osman, ZB Harris… - Journal of …, 2022 - spiedigitallibrary.org
Significance Severe burn injuries cause significant hypermetabolic alterations that are
highly dynamic, hard to predict, and require acute and critical care. The clinical assessments …

[HTML][HTML] Assessing corneal endothelial damage using terahertz time-domain spectroscopy and support vector machines

A Chen, ZB Harris, A Virk, A Abazari, K Varadaraj… - Sensors, 2022 - mdpi.com
The endothelial layer of the cornea plays a critical role in regulating its hydration by actively
controlling fluid intake in the tissue via transporting the excess fluid out to the aqueous …

Polarimetric imaging of back-scattered terahertz speckle fields using a portable scanner

K Xu, ZB Harris, MH Arbab - Optics Express, 2023 - opg.optica.org
Speckle patterns observed in coherent optical imaging reflect important characteristic
information of the scattering object. To capture speckle patterns, angular resolved or oblique …

[HTML][HTML] Label-free detection and identification of single bacteria via terahertz near-field imaging

J Wang, L Peng, D Han, T Zheng, T Chang… - Frontiers in …, 2023 - frontiersin.org
In recent years, terahertz (THz) imaging has attracted much attention because of its ability to
obtain physical and chemical information in a label-free, noninvasive and nonionizing …