miRNAs as potential diagnostic biomarkers and pharmacogenomic indicators in psychiatric disorders
EE Tsermpini, CI Kalogirou… - The …, 2022 - nature.com
The heterogeneity of psychiatric disorders and the lack of reliable biomarkers for prediction
and treatments follow-up pose difficulties towards recognition and understanding of the …
and treatments follow-up pose difficulties towards recognition and understanding of the …
Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives
S Jiao, T Cao, H Cai - Frontiers in Pharmacology, 2022 - frontiersin.org
Treatment-resistant schizophrenia (TRS) often results in severe disability and functional
impairment. Currently, the diagnosis of TRS is largely exclusionary and emphasizes the …
impairment. Currently, the diagnosis of TRS is largely exclusionary and emphasizes the …
Loperamide, a peripheral Mu-Opioid receptor agonist, attenuates chemotherapy-induced neuropathic pain in rats
Opioids are employed in the management of chemotherapy-induced neuropathic pain
(CINP) when other pain management approaches have failed and proven ineffective …
(CINP) when other pain management approaches have failed and proven ineffective …
Remote ischemic conditioning alleviates chronic cerebral hypoperfusion-induced cognitive decline and synaptic dysfunction via the miR-218a-5p/SHANK2 pathway
N Li, C Ren, S Li, W Yu, K Jin, X Ji - Progress in Neurobiology, 2023 - Elsevier
Vascular cognitive impairment (VCI) due to chronic cerebral hypoperfusion (CCH), is the
second leading cause of dementia. Although synaptic impairment plays a critical role in VCI …
second leading cause of dementia. Although synaptic impairment plays a critical role in VCI …
Treatment-resistant schizophrenia, clozapine resistance, genetic associations, and implications for precision psychiatry: a scoping review
Treatment-resistant schizophrenia (TRS) is often associated with severe burden of disease,
poor quality of life and functional impairment. Clozapine is the gold standard for the …
poor quality of life and functional impairment. Clozapine is the gold standard for the …
miR-218-2 regulates cognitive functions in the hippocampus through complement component 3–dependent modulation of synaptic vesicle release
SY Lu, CL Fu, L Liang, B Yang… - Proceedings of the …, 2021 - National Acad Sciences
microRNA-218 (miR-218) has been linked to several cognition related neurodegenerative
and neuropsychiatric disorders. However, whether miR-218 plays a direct role in cognitive …
and neuropsychiatric disorders. However, whether miR-218 plays a direct role in cognitive …
[HTML][HTML] Application of miRNA-seq in neuropsychiatry: A methodological perspective
D Pérez-Rodríguez, H López-Fernández… - Computers in Biology …, 2021 - Elsevier
MiRNAs are emerging as key molecules to study neuropsychiatric diseases. However,
despite the large number of methodologies and software for miRNA-seq analyses, there is …
despite the large number of methodologies and software for miRNA-seq analyses, there is …
[HTML][HTML] Extracellular microRNAs associated with psychiatric symptoms in the Normative Aging Study
Earlier studies have revealed microRNAs (miRNAs) as potential biomarkers for neurological
conditions, however, such evidence on psychiatric outcomes is limited. We utilized the …
conditions, however, such evidence on psychiatric outcomes is limited. We utilized the …
[HTML][HTML] The Role of microRNA in Schizophrenia: A Scoping Review
K Li, L Zhu, H Lv, Y Bai, C Guo, K He - International Journal of Molecular …, 2024 - mdpi.com
Schizophrenia is a serious mental disease that is regulated by multiple genes and
influenced by multiple factors. Due to the complexity of its etiology, the pathogenesis is still …
influenced by multiple factors. Due to the complexity of its etiology, the pathogenesis is still …
Pharmacogenetic intervention improves treatment outcomes in Chinese adult men with schizophrenia
Y Qin, Y Liu, J Zhao, Y Yang, H Xiang, T Gao… - Journal of Psychiatric …, 2024 - Elsevier
To investigate the clinical application value of pharmacogenetic testing in individualized
drug therapy for adult male patients with schizophrenia. A total of 186 adult patients with …
drug therapy for adult male patients with schizophrenia. A total of 186 adult patients with …