Abstract Tumour Necrosis Factor α (TNFα), is an inflammatory cytokine produced by
macrophages/monocytes during acute inflammation and is responsible for a diverse range …

Cisplatin is a highly effective antitumor agent whose clinical application is limited by the
inherent nephrotoxicity. The current measures of nephroprotection used in patients receiving …

Periodontal disease is the most frequent cause of tooth loss in humans and is the most
prevalent disease associated with bone loss, including osteoporosis. Periodontal …

Through its type 1 receptor (TNFR1), the cytokine TNF elicits an unusually wide range of
biological responses, including inflammation, tumor necrosis, cell proliferation …

Severe and prolonged impairment of mitochondrial β-oxidation leads to microvesicular
steatosis, and, in severe forms, to liver failure, coma and death. Impairment of mitochondrial …

Traumatic brain injury (TBI) is a major healthcare concern, constituting a major cause of
death and disability throughout the world. Among the factors leading to TBI outcome are …

Tumour necrosis factor (TNF) exerts two main effects: a beneficial one as an anti-infection,
anti-tumour cytokine, and a detrimental one in the systemic inflammatory response …

Nuclear factor-κB (NF-κB) regulates the transcription of a variety of genes involved in
immune responses, cell growth, and cell death. However, the role of NF-κB in muscle …

Nuclear factor kappa-B (NFκB), a redox-sensitive transcription factor regulating a battery of
inflammatory genes, has been indicated to play a role in the development of numerous …

Increasing attention is being paid to the role of inflammatory and immune molecules in the
modulation of central nervous system (CNS) function. Tumour necrosis factor‐α (TNF‐α) is a …