This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Photodynamic therapy is considered as a promising treatment for cancer, but still faces
several challenges. The hypoxic environment in solid tumors, imprecise tumor recognition …

Hypoxia is a hallmark of many solid tumors, and it causes the overexpression of a variety of
proteins including the epidermal growth factor receptor (EGFR). Many antitumor prodrugs …

Nitroreductase (NTR) activities have been known for decades, studied extensively in
bacteria and also in systems as diverse as yeast, trypanosomes, and hypoxic tumors. The …

As one of the most representative hypoxic enzymes, nitroreductases (NTRs) play
momentous roles in malignant tumor progression, metastasis, invasion and angiogenesis …

Azo dyes are widely used in textile, fiber, cosmetic, leather, paint and printing industries.
Besides their characteristic coloring function, azo compounds are reported as antibacterial …

The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …

The use of nonfluorescent azo dyes as dark quenchers in activatable optical bioprobes
based on the Förster resonance energy transfer (FRET) mechanism and designed to target …