[HTML][HTML] A narrative review on trans-nasal pulmonary aerosol delivery

J Li, JB Fink, R MacLoughlin, R Dhand - Critical Care, 2020 - Springer
The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has
expanded in recent years. However, various factors influencing aerosol delivery in this …

[HTML][HTML] High-flow nasal cannula oxygen therapy: physiological mechanisms and clinical applications in children

S Nolasco, S Manti, S Leonardi, C Vancheri… - Frontiers in …, 2022 - frontiersin.org
High-flow nasal cannula (HFNC) oxygen therapy has rapidly become a popular modality of
respiratory support in pediatric care. This is undoubtedly due to its ease of use and safety …

The influence of changing interfaces on aerosol delivery within high flow oxygen setting in adults: an in-vitro study

YM Madney, NI Laz, AA Elberry, H Rabea… - Journal of Drug Delivery …, 2020 - Elsevier
Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

Variation in practice related to the use of high flow nasal cannula in critically ill children

A Kawaguchi, D Garros, A Joffe… - Pediatric Critical Care …, 2020 - journals.lww.com
Objectives: To determine current management of critically ill children and gather views
regarding high flow nasal cannula therapy and to evaluate research priorities for a large …

[HTML][HTML] Comparison of aerosol delivery across combinations of drug delivery interfaces with and without concurrent high-flow nasal therapy

G Bennett, M Joyce, EF Fernández… - Intensive care medicine …, 2019 - Springer
Background Current clinical practice during high-flow nasal therapy (HFNT) involves
utilization of a nasal cannula to provide humidification, with a facemask placed over the …

Individualized aerosol medicine: Integrating device into the patient

A Ari, N Raghavan, M Diaz, BK Rubin… - Paediatric Respiratory …, 2023 - Elsevier
Pulmonary drug delivery is complex due to several challenges including disease-, patient-,
and clinicians-related factors. Although many inhaled medications are available in aerosol …

Decrease the flow setting to improve trans‐nasal pulmonary aerosol delivery via “high‐flow nasal cannula” to infants and toddlers

J Li, L Gong, A Ari, JB Fink - Pediatric Pulmonology, 2019 - Wiley Online Library
Objectives Trans‐nasal pulmonary aerosol delivery for infants and toddlers has recently
gained popularity, however, the reported lung deposition is low. We aimed to investigate the …

Worldwide clinical practice of high-flow nasal cannula and concomitant aerosol therapy in the adult ICU setting

J Li, M Tu, L Yang, G Jing, JB Fink, C Burtin… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: High-flow nasal cannula (HFNC) oxygen therapy has been broadly used.
However, no consensus has been achieved on the practical implementation of HFNC and …

[HTML][HTML] The ratio of nasal cannula gas flow to patient inspiratory flow on trans-nasal pulmonary aerosol delivery for adults: an in vitro study

J Li, L Gong, JB Fink - Pharmaceutics, 2019 - mdpi.com
Trans-nasal aerosol deposition during distressed breathing is higher than quiet breathing,
and decreases as administered gas flow increases. We hypothesize that inhaled dose is …

Aerosol delivery in models of pediatric high flow nasal oxygen and mechanical ventilation

R Wang, CO Leime, W Gao… - Pediatric …, 2023 - Wiley Online Library
Background Aerosol drug delivery during high flow nasal oxygen (HFNO) and invasive
mechanical ventilation (IMV) are key respiratory care strategies available for the treatment of …