Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

Extrahepatic cholangiocarcinoma (eCCA) contains perihilar cholangiocarcinoma and distal
cholangiocarcinoma both of which can arise at any point of the biliary tree and originate from …

Cholangiocarcinoma (CCA) represents a heterogenous set of malignancies arising from the
biliary tract. Classification of CCA subdivides tumours into intrahepatic (iCCA) and …

Background & Aims Cholangiocarcinoma (CCA) is a primary liver tumour characterised by a
poor prognosis and limited therapeutic options. Available 3D human CCA models fail to …

Cholangiocarcinoma (CCA) is an aggressive cancer associated with a very poor prognosis
and low survival rates, primarily due to late-stage diagnosis and low response rates to …

Intrahepatic cholangiocarcinoma (ICC) is a form of liver cancer with poor long-term survival
rates that requires novel therapeutic methods. Our team's previous research found that ICC …

As two major types of primary liver cancers, the tumor immune microenvironment (TIME) of
hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) have been well …

Cholangiocarcinoma (CCA) is a rare malignancy of the gastrointestinal tract, with aggressive
behavior, and portends a poor prognosis. Traditionally, it is classified according to its site of …

Gastrointestinal (GI) tumors are a significant global health threat, with high rates of morbidity
and mortality. Exosomes contain various biologically active molecules like nucleic acids …

Heavy alcohol intake induces a wide spectrum of liver diseases ranging from steatosis,
steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Although alcohol …