[HTML][HTML] The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

[HTML][HTML] Long non-coding RNA and RNA-binding protein interactions in cancer: Experimental and machine learning approaches

H Shaath, R Vishnubalaji, R Elango… - Seminars in Cancer …, 2022 - Elsevier
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

LncRNA–FEZF1-AS1 promotes tumor proliferation and metastasis in colorectal cancer by regulating PKM2 signaling

Z Bian, J Zhang, M Li, Y Feng, X Wang, J Zhang… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: Long non-coding RNAs (lncRNAs) play key roles in human cancers. Here,
FEZF1-AS1, a highly overexpressed lncRNA in colorectal cancer, was identified by lncRNA …

[HTML][HTML] LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside

Q Hu, H Ma, H Chen, Z Zhang, Q Xue - Cell death discovery, 2022 - nature.com
Lung cancer has been one of the leading causes of cancer-related death worldwide, and
non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer morbidity, yet …

Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs

W Jiang, J Xia, S Xie, R Zou, S Pan, Z Wang… - Drug Resistance …, 2020 - Elsevier
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

[HTML][HTML] Expanding the role of the histone lysine-specific demethylase LSD1 in cancer

B Majello, F Gorini, CD Saccà, S Amente - Cancers, 2019 - mdpi.com
Studies of alterations in histone methylation in cancer have led to the identification of histone
methyltransferases and demethylases as novel targets for therapy. Lysine-specific …

Long non‐coding RNAs in cancer: another layer of complexity

JC de Oliveira, LC Oliveira, C Mathias… - The journal of gene …, 2019 - Wiley Online Library
We review the most well characterized long non‐coding RNAs (lncRNAs) with important
roles in hallmarks of cancer, additionally including lncRNAs with a higher potential for …

[HTML][HTML] Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis

A Acha-Sagredo, B Uko, P Pantazi, NG Bediaga… - British journal of …, 2020 - nature.com
Abstract Background Long non-coding RNAs compose an important level of epigenetic
regulation in normal physiology and disease. Despite the plethora of publications of …

[HTML][HTML] LncRNAs in non-small-cell lung cancer

L Ginn, L Shi, M La Montagna, M Garofalo - Non-coding RNA, 2020 - mdpi.com
Lung cancer is associated with a high mortality, with around 1.8 million deaths worldwide in
2018. Non-small-cell lung cancer (NSCLC) accounts for around 85% of cases and, despite …

Lysine-specific demethylase 1 promises to be a novel target in cancer drug resistance: therapeutic implications

FF Yang, XL Xu, T Hu, JQ Liu, JZ Zhou… - Journal of Medicinal …, 2023 - ACS Publications
Chemotherapy, targeted therapy, and immunotherapy are effective against most tumors, but
drug resistance remains a barrier to successful treatment. Lysine-specific demethylase 1 …