Diagnosis and pharmacotherapy of alcohol use disorder: a review

HR Kranzler, M Soyka - Jama, 2018 - jamanetwork.com
Importance Alcohol consumption is associated with 88 000 US deaths annually. Although
routine screening for heavy alcohol use can identify patients with alcohol use disorder …

Neuroscience of addiction: relevance to prevention and treatment

ND Volkow, M Boyle - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …

Alcohol use disorder: neurobiology and therapeutics

W Yang, R Singla, O Maheshwari, CJ Fontaine… - Biomedicines, 2022 - mdpi.com
Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits
involved in executive function leading to excessive consumption of alcohol, despite negative …

Gabapentin: abuse, dependence, and withdrawal

TL Mersfelder, WH Nichols - Annals of Pharmacotherapy, 2016 - journals.sagepub.com
Objective: To identify case reports and studies regarding patients who abused, became
dependent on, or experienced withdrawal from gabapentin. Data Sources: A PubMed …

A meta‐analysis of the efficacy of gabapentin for treating alcohol use disorder

HR Kranzler, R Feinn, P Morris, EE Hartwell - Addiction, 2019 - Wiley Online Library
Abstract Background and Aims Studies of the efficacy of gabapentin for treating alcohol use
disorder (AUD) have yielded mixed findings. The aims of our study were to estimate …

Evidence-based pharmacotherapies for alcohol use disorder: clinical pearls

J Fairbanks, A Umbreit, BP Kolla, VM Karpyak… - Mayo Clinic …, 2020 - Elsevier
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all
deaths worldwide. There are three medications approved for the treatment of alcohol use …

Gabapentin for the treatment of alcohol use disorder

BJ Mason, S Quello, F Shadan - Expert opinion on investigational …, 2018 - Taylor & Francis
Introduction: Alcohol misuse is the fifth leading risk factor for premature death and disability
worldwide. Fewer than 10% of afflicted Americans receive pharmacological treatment for …

Pharmacotherapy of alcoholism–an update on approved and off-label medications

M Soyka, CA Müller - Expert Opinion on Pharmacotherapy, 2017 - Taylor & Francis
Introduction: Only a few medications are available for the treatment of alcohol use disorders
(AUDs). Areas covered: This paper discusses approved AUD medications, including the …

Cannabidiol as a novel candidate alcohol use disorder pharmacotherapy: a systematic review

J Turna, SK Syan, BN Frey, B Rush… - Alcoholism: Clinical …, 2019 - Wiley Online Library
There is substantial interest in the therapeutic potential of cannabidiol (CBD), a
nonpsychoactive cannabinoid found in plants of the genus Cannabis. The goal of the current …

Management of alcohol withdrawal in the emergency department: current perspectives

C Wolf, A Curry, J Nacht… - Open Access Emergency …, 2020 - Taylor & Francis
Alcohol withdrawal syndrome (AWS) is a common, heterogenous, and life-threatening
complication of alcohol use disorder (AUD). AUD is a leading cause of worldwide mortality …