Pharmacotherapy of alcoholism–an update on approved and off-label medications

M Soyka, CA Müller - Expert Opinion on Pharmacotherapy, 2017 - Taylor & Francis
Introduction: Only a few medications are available for the treatment of alcohol use disorders
(AUDs). Areas covered: This paper discusses approved AUD medications, including the …

The ASAM clinical practice guideline on alcohol withdrawal management

A Alvanzo, K Kleinschmidt, JA Kmiec - J Addict Med, 2020 - journals.lww.com
I. Purpose The American Society of Addiction Medicine (ASAM) developed this Guideline on
Alcohol Withdrawal Management to provide updated information on evidence-based …

Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review

PV Fischler, M Soyka, E Seifritz… - Frontiers in …, 2022 - frontiersin.org
Compounds known to be successful in the treatment of alcohol use disorder include the
aversive agent, Disulfiram, the glutamatergic NMDA receptor antagonist, Acamprosate, and …

Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision

M Soyka, HR Kranzler, V Hesselbrock… - The World Journal of …, 2017 - Taylor & Francis
These practice guidelines for the biological treatment of alcohol use disorders are an update
of the first edition, published in 2008, which was developed by an international Task Force of …

Integrated care of alcohol-related liver disease

GS Winder, AC Fernandez, JL Mellinger - Journal of Clinical and …, 2022 - Elsevier
Background/Aims Alcohol-related liver disease (ALD) is the medical manifestation of alcohol
use disorder, a prevalent psychiatric condition. Acute and chronic manifestations of ALD …

Medications for alcohol use disorder

BT Winslow, M Onysko, M Hebert - American family physician, 2016 - aafp.org
The US Preventive Services Task Force recommends that clinicians screen adults for
alcohol misuse and provide persons engaged in risky or hazardous drinking behaviors with …

Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta‐analysis

A Bahji, P Bach, M Danilewitz, D Crockford… - …, 2022 - Wiley Online Library
Abstract Background and Aims There have been few head‐to‐head clinical trials of
pharmacotherapies for alcohol withdrawal (AW). We, therefore, aimed to evaluate the …

Phenibut: review and pharmacologic approaches to treating withdrawal

SR Penzak, M Bulloch - The Journal of Clinical Pharmacology, 2024 - Wiley Online Library
Abstract β‐Phenyl‐γ‐aminobutyric acid (phenibut) is an analog of the inhibitory
neurotransmitter γ‐aminobutyric acid (GABA) that was first synthesized in Russia in the early …

The spectrum of alcohol use: epidemiology, diagnosis, and treatment

SM Cohen, RS Alexander, SR Holt - Medical Clinics, 2022 - medical.theclinics.com
Alcohol is the most commonly used and misused substance in the United States (US)(Table
1). 1 More than 50% of the US population report past month alcohol use and more than 85 …

Emergency department management of patients with alcohol intoxication, alcohol withdrawal, and alcohol use disorder: a white paper prepared for the American …

RJ Strayer, BW Friedman, R Haroz, E Ketcham… - The Journal of …, 2023 - Elsevier
Alcohol is the most-used intoxicant in the world, and the repercussions of unhealthy alcohol
use are of corresponding magnitude. A sixfold increase in all-cause mortality and 6% of …