Protective effects of estrogen via nanoparticle delivery to attenuate myelin loss and neuronal death after spinal cord injury

A Haque, KP Drasites, A Cox, M Capone… - Neurochemical …, 2021 - Springer
Spinal cord injury (SCI) is associated with devastating neurological deficits affecting more
than 11,000 Americans each year. Although several therapeutic agents have been …

[HTML][HTML] Indometacin inhibits the proliferation and activation of human pancreatic stellate cells through the downregulation of COX-2

L Sun, K Chen, Z Jiang, X Chen, J Ma… - Oncology …, 2018 - spandidos-publications.com
Increasing evidence indicates that pancreatic stellate cells (PSCs) are responsible for the
stromal reaction in pancreatic ductal adenocarcinoma (PDAC). The interaction between …

Pro-apoptotic effect of methylguanidine on hydrogen peroxide-treated rat glioma cell line

S Marzocco, A Popolo, G Bianco, A Pinto… - Neurochemistry …, 2010 - Elsevier
Guanidino compounds, as methylguanidine (MG), may play an important role in the etiology
of neurological complications which occur in uremic syndrome. Dementia is a neurological …

Indometacin ameliorates high glucose-induced proliferation and invasion via modulation of e-cadherin in pancreatic cancer cells

L Han, B Peng, Q Ma, J Ma, J Li, W Li… - Current medicinal …, 2013 - ingentaconnect.com
Indometacin, an inhibitor of cyclooxygenase-2 (COX-2), has been shown to exert anticancer
effects in a variety of cancers. However, the effect and mechanism of indometacin on high …

Indomethacin decreases insulin secretion by reducing KCa3. 1 as a biomarker of pancreatic tumor and causes apoptotic cell death

A Karatug Kacar - Journal of Biochemical and Molecular …, 2020 - Wiley Online Library
Insulinomas originate from pancreatic β cells and it is the most widely known tumor.
Indomethacin is a nonsteroidal anti‐inflammatory drug, which is used for blocking the …

[PDF][PDF] 替莫唑胺及甲泼尼龙对人胶质瘤细胞放射治疗敏感性的影响

李瑜, 杨学军, 曹永珍, 元大发… - 中国现代神经 …, 2011 - journal11.magtechjournal.com
目的探讨替莫唑胺(TMZ) 和甲泼尼龙(MP) 对人胶质瘤细胞系U251 放射治疗敏感性的影响,
以期为临床优化治疗方案提供依据. 方法经体外传代培养的U251 细胞根据治疗方案的不同 …

Glucocorticoid Pharmacotoxicological Interactions and Modulation of Toxicity

QM Chen, H Sun - Adrenal Toxicology, 2008 - taylorfrancis.com
The historical breakthrough of glucocorticoids as a pharmacological agent can be traced
back to 1929. At the time, Dr. Philip S. Hench developed the concept that steroids could …