The beneficial role of autophagy in multiple sclerosis: yes or no?
Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …
[HTML][HTML] Autophagy orchestrates resistance in hepatocellular carcinoma cells
Abstract Treatment resistance is one of the major barriers for therapeutic strategies in
hepatocellular carcinoma (HCC). Many studies have indicated that chemotherapy and …
hepatocellular carcinoma (HCC). Many studies have indicated that chemotherapy and …
Autophagy-targeted calcium phosphate nanoparticles enable transarterial chemoembolization for enhanced cancer therapy
Transarterial chemoembolization (TACE) is commonly used for treating advanced
hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and the …
hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and the …
Magnesium/gallium-layered nanosheets on titanium implants mediate osteogenic differentiation of MSCs and osseointegration under osteoporotic condition
M Chen, Y Hu, Y Hou, M Li, L Tan, M Chen… - Chemical Engineering …, 2022 - Elsevier
Osteoporotic fracture is generally hard to be fixed due to its abnormal microenvironment and
cells metabolism, leading to poor osteointegration between the implants and surrounding …
cells metabolism, leading to poor osteointegration between the implants and surrounding …
HBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progression
C Zheng, M Liu, Y Ge, Y Qian, H Fan - Cell Death & Disease, 2022 - nature.com
Hepatitis B virus (HBV) infection is the predominant causes of hepatocellular carcinoma
(HCC). HBV X protein (HBx), as the most frequently integrated viral gene sequence …
(HCC). HBV X protein (HBx), as the most frequently integrated viral gene sequence …
Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression
XP Tan, Y He, J Yang, X Wei, YL Fan… - … and Targeted Therapy, 2023 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Identification
of the underlying mechanism of HCC progression and exploration of new therapeutic drugs …
of the underlying mechanism of HCC progression and exploration of new therapeutic drugs …
Hepatocellular carcinoma cells loss lenvatinib efficacy in vitro through autophagy and hypoxia response-derived neuropilin-1 degradation
P Fernández-Palanca, T Payo-Serafín… - Acta pharmacologica …, 2023 - nature.com
Despite pharmacological advances such as lenvatinib approval, therapeutic failure of
hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its …
hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its …
[HTML][HTML] Stachydrine hydrochloride inhibits hepatocellular carcinoma progression via LIF/AMPK axis
X Bao, Y Liu, J Huang, S Yin, H Sheng, X Han, Q Chen… - Phytomedicine, 2022 - Elsevier
Background: Hepatocellular carcinoma (HCC) is not only one of the four highest
malignancies, but also the principal reason of cancer-related death worldwide, yet no …
malignancies, but also the principal reason of cancer-related death worldwide, yet no …
Hydrogen sulfide and liver health: insights into liver diseases
TTP Nguyen, PL Nguyen, SH Park… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Hydrogen sulfide (H2S) is a recently recognized gasotransmitter involved in
physiological and pathological conditions in mammals. It protects organs from oxidative …
physiological and pathological conditions in mammals. It protects organs from oxidative …
[HTML][HTML] Combating drug resistance in hepatocellular carcinoma: No awareness today, no action tomorrow
F Jing, X Li, H Jiang, J Sun, Q Guo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide, is associated
with a high degree of malignancy and poor prognosis. Patients with early HCC may benefit …
with a high degree of malignancy and poor prognosis. Patients with early HCC may benefit …