A framework to advance biomarker development in the diagnosis, outcome prediction, and treatment of traumatic brain injury
EA Wilde, IB Wanner, K Kenney, J Gill… - Journal of …, 2022 - liebertpub.com
Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
Thorough overview of ubiquitin C‐terminal hydrolase‐L1 and glial fibrillary acidic protein as tandem biomarkers recently cleared by US Food and Drug Administration …
Traumatic brain injury (TBI) is a major cause of mortality and morbidity affecting all ages. It
remains to be a diagnostic and therapeutic challenge, in which, to date, there is no Food and …
remains to be a diagnostic and therapeutic challenge, in which, to date, there is no Food and …
Remote blood biomarkers of longitudinal cognitive outcomes in a population study
Objective The longitudinal association of the blood biomarkers total tau (t‐tau),
neurofilament light (Nf‐L), and glial fibrillary acidic protein (GFAP) with common sporadic …
neurofilament light (Nf‐L), and glial fibrillary acidic protein (GFAP) with common sporadic …
Epidemiology of concussions in national collegiate athletic association (NCAA) sports: 2014/15-2018/19
A Chandran, AJ Boltz, SN Morris… - … American Journal of …, 2022 - journals.sagepub.com
Background: Updated epidemiology studies examining sports-related concussions (SRCs)
are critical in evaluating recent efforts aimed at reducing the incidence of SRCs in National …
are critical in evaluating recent efforts aimed at reducing the incidence of SRCs in National …
Colloidal gold-based immunochromatographic biosensor for quantitative detection of S100B in serum samples
Traumatic brain injury has become a serious public health problem. Timely detection,
diagnosis and treatment of brain injury are closely related to the prognosis of patients, so …
diagnosis and treatment of brain injury are closely related to the prognosis of patients, so …
Association of CSF and serum neurofilament light and glial fibrillary acidic protein, injury severity, and outcome in spinal cord injury
Background and Objectives Traumatic spinal cord injury (SCI) is highly heterogeneous, and
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
[HTML][HTML] The current state of traumatic brain injury biomarker measurement methods
Traumatic brain injury (TBI) is associated with high rates of morbidity and mortality partially
due to the limited tools available for diagnosis and classification. Measuring panels of …
due to the limited tools available for diagnosis and classification. Measuring panels of …
[HTML][HTML] Perspectives on primary blast injury of the brain: translational insights into non-inertial low-intensity blast injury
Most traumatic brain injuries (TBIs) during military deployment or training are clinically “mild”
and frequently caused by non-impact blast exposures. Experimental models were …
and frequently caused by non-impact blast exposures. Experimental models were …
[HTML][HTML] One-year prospective study of plasma biomarkers from CNS in patients with mild traumatic brain injury
GJB Clarke, T Skandsen, H Zetterberg… - Frontiers in …, 2021 - frontiersin.org
Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament
light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized …
light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized …
Serum tau, neurofilament light chain, glial fibrillary acidic protein, and ubiquitin carboxyl-terminal hydrolase L1 are associated with the chronic deterioration of …
RT Lange, S Lippa, TA Brickell, J Gill… - Journal of …, 2023 - liebertpub.com
The purpose of this study was to examine the association of serum tau, neurofilament light
chain (NFL), glial fibrillary acidic protein (GFAP), and ubiquitin carboxy-terminal hydrolase …
chain (NFL), glial fibrillary acidic protein (GFAP), and ubiquitin carboxy-terminal hydrolase …