Until recently, the development of new human adjuvants was held back by a poor
understanding of their mechanisms of action. The field was revolutionized by the discovery …

The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …

GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …

Infections of the central nervous system are among the most serious infections,, but the
mechanisms by which pathogens access the brain remain poorly understood. The model …

Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

Macrophage polarization plays an important role in the progression of inflammation.
Exosomes derived from stem cells are promising candidates for macrophage …

Tuberculosis (TB), an important issue in the present age, affects millions of people each
year. The infectious agent of TB, Mycobacterium tuberculosis (Mtb), interacts with the …

Coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is an infectious disease
that poses severe threats to global public health and significant economic losses. The …

Knowledge of glycogen synthase kinase 3β (GSK3β) activity and the molecules identified
that regulate its function in infections caused by pathogenic microorganisms is crucial to …

Despite remarkable success in the prevention and treatment of tuberculosis (TB), it remains
one of the most devastating infectious diseases worldwide. Management of TB requires an …