Normal cells explore multiple states to survive stresses encountered during development
and self-renewal as well as environmental stresses such as starvation, DNA damage, toxins …

IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

As a point of convergence for numerous oncogenic signaling pathways, signal transducer
and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune …

Colorectal cancers (CRCs) with deficient mismatch repair (dMMR) or microsatellite instability-
high (MSI-H) often have sustained responses to immune checkpoint inhibitors (ICIs) …

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …

Microalgae are photosynthetic microorganisms adapted to live in very different environments
and showing an enormous biochemical and genetic diversity, thus representing an excellent …

For patients with non-small-cell lung cancer (NSCLC) tumors without currently targetable
molecular alterations, standard-of-care treatment is immunotherapy with anti-PD-(L) 1 …

Excessive activation of signal transducer and activator of transcription 3 (STAT3) signaling is
observed in a subset of many cancers, making activated STAT3 a highly promising potential …

Signal transducer and activator of transcription 3 (STAT3) is a critical transcription factor that
has been firmly associated with colorectal cancer (CRC) initiation and development. STAT3 …

Glioblastoma belongs to the most malignant intracranial tumors characterized by
indispensable growth and aggressiveness that highly associates with dismal prognosis and …