Immunotherapy is a promising treatment strategy for cancer that has recently shown
unprecedented survival benefits in selected patients. A number of immunomodulatory …

Background Autologous NK cell therapy can treat a variety of malignancies, but is limited by
patient-specific variations in potency and cell number expansion. In contrast, allogeneic NK …

PURPOSE: To predict programmed death-ligand 1 (PD-L1) expression of tumor cells in non-
small cell lung cancer (NSCLC) patients by using a radiomics study based on CT images …

To assess if quantitative integrated deep learning and radiomics features can predict the PD-
L1 expression level in preoperative MRI of hepatocellular carcinoma (HCC) patients. The …

Immune checkpoint inhibitors (ICIs), represented by anti-CTLA-4 or anti-PD-1/anti-PD-L1
pathway antibodies, have led to a revolution in cancer treatment modalities. ICIs have …

Recently, it has been described that programmed cell death protein 1 (PD-1) overexpressing
melanoma cells are highly aggressive. However, until now it has not been defined which …

Abstract Attenuated Listeria monocytogenes (Lmat-LLO) represents a valuable anticancer
vaccine and drug delivery platform. Here we show that in vitro Lmat-LLO causes ROS …

Doxycycline is a semisynthetic, second generation tetracycline. Currently, it is used, among
others, in the treatment of acne and skin infections. Moreover, doxycycline has many …

Background Patients receiving novel treatments like immune checkpoint inhibitor therapy
(ICI or immunotherapy) to treat their cancer require comprehensive information so they know …

New Zealand has one of the highest rates of melanoma in the world. In up to 10% of cases,
the disease is metastatic at diagnosis. Cerebral metastatic involvement carries a particularly …