Objective: The aim of the present study was to assess the association between HLA-DRB1
and-DQB1 allele groups with the genetic predisposition to multiple sclerosis (MS) in the …

Objective: The major histocompatibility complex (MHC) is the primary genetic contributor to
multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE), but multiple …

Multiple sclerosis (MS) is an autoimmune neuroinflammatory disease where the underlying
mechanisms driving disease progression have remained unresolved. HLA-DR2b (DRB1 …

Abstract Background Epstein–Barr virus (EBV) infection is implicated with multiple sclerosis
(MS) risk, exacerbation, and progression. The HLA-DRB1* 1501 haplotype is a strong MS …

Objective: The aim of this study was to determine ancestry informative markers,
mitochondrial DNA haplogroups, and the association between HLA-DRB1 alleles and …

Background Multiple sclerosis (MS) is an autoimmune demyelinating disease affecting
mostly young adult females with multifactorial etiology. Recent studies suggested that …

Multiple Sclerosis (MS) is a complex chronic neurodegenerative disorder resulting from an
autoimmune reaction against myelin. So far, many genetic variants have been reported to …

We investigated association between HLA class I and class II alleles and haplotypes, and
KIR loci and their HLA class I ligands, with multiple sclerosis (MS) in 412 European …

Multiple Sclerosis is a chronic, progressive and debilitating neurological disease which,
despite extensive study for over 100 years, remains of enigmatic aetiology. Drawn from the …

Antigen presentation is a crucial mechanism that drives the T cell-mediated immune
response and the development of Multiple Sclerosis (MS). Genetic alterations within the …