Functional dissection of synaptic circuits: in vivo patch-clamp recording in neuroscience

C Tao, G Zhang, Y Xiong, Y Zhou - Frontiers in neural circuits, 2015 - frontiersin.org
Neuronal activity is dominated by synaptic inputs from excitatory or inhibitory neural circuits.
With the development of in vivo patch-clamp recording, especially in vivo voltage-clamp …

Identifying neuron types and circuit mechanisms in the auditory midbrain

AC Drotos, MT Roberts - Hearing Research, 2023 - Elsevier
The inferior colliculus (IC) is a critical computational hub in the central auditory pathway.
From its position in the midbrain, the IC receives nearly all the ascending output from the …

Mammalian octopus cells are direction selective to frequency sweeps by excitatory synaptic sequence detection

HW Lu, PH Smith, PX Joris - Proceedings of the National …, 2022 - National Acad Sciences
Octopus cells are remarkable projection neurons of the mammalian cochlear nucleus, with
extremely fast membranes and wide-frequency tuning. They are considered prime examples …

Rapid spectrotemporal plasticity in primary auditory cortex during behavior

P Yin, JB Fritz, SA Shamma - Journal of Neuroscience, 2014 - Soc Neuroscience
Complex natural and environmental sounds, such as speech and music, convey information
along both spectral and temporal dimensions. The cortical representation of such stimuli …

Recurrent network dynamics shape direction selectivity in primary auditory cortex

DA Aponte, G Handy, AM Kline, H Tsukano… - Nature …, 2021 - nature.com
Detecting the direction of frequency modulation (FM) is essential for vocal communication in
both animals and humans. Direction-selective firing of neurons in the primary auditory cortex …

Identified GABAergic and glutamatergic neurons in the mouse inferior colliculus share similar response properties

M Ono, DC Bishop, DL Oliver - Journal of Neuroscience, 2017 - Soc Neuroscience
GABAergic neurons in the inferior colliculus (IC) play a critical role in auditory information
processing, yet their responses to sound are unknown. Here, we used optogenetic methods …

Neuronal activity in sensory cortex predicts the specificity of learning in mice

KC Wood, CF Angeloni, K Oxman, C Clopath… - Nature …, 2022 - nature.com
Learning to avoid dangerous signals while preserving normal responses to safe stimuli is
essential for everyday behavior and survival. Following identical experiences, subjects …

Retinal direction selectivity in the absence of asymmetric starburst amacrine cell responses

L Hanson, S Sethuramanujam, G deRosenroll, V Jain… - Elife, 2019 - elifesciences.org
In the mammalian retina, direction-selectivity is thought to originate in the dendrites of
GABAergic/cholinergic starburst amacrine cells, where it is first observed. However, here we …

Encoding of ultrasonic vocalizations in the auditory cortex

IM Carruthers, RG Natan… - Journal of …, 2013 - journals.physiology.org
One of the central tasks of the mammalian auditory system is to represent information about
acoustic communicative signals, such as vocalizations. However, the neuronal computations …

[HTML][HTML] Interaural level difference-dependent gain control and synaptic scaling underlying binaural computation

XR Xiong, F Liang, H Li, L Mesik, KK Zhang, DB Polley… - Neuron, 2013 - cell.com
Binaural integration in the central nucleus of inferior colliculus (ICC) plays a critical role in
sound localization. However, its arithmetic nature and underlying synaptic mechanisms …