Antibody-drug conjugates are gradually revolutionizing anticancer therapy. Payload is one
of the most crucial components of ADC for high antitumor activity. However, there is no direct …

The targeting dual-responsive intelligent drug delivery system has been employed for
cancer treatment as a positive strategy. Herein, we synthesized anisamide-modified …

A fluorescent probe for protease sensing and based on the “covalent-assembly” principle is
reported. The basic rational for this unusual class of chemodosimeters proposed by the …

A novel one-and two-photon fluorescent probe based on a photoreaction was developed for
the detection of cysteine (Cys). After it was reacted with Cys and illuminated by light, a strong …

A simple and effective biocompatible domino reaction triggered by a model protease and
leading to the formation of strongly fluorescent quinoxalin-2 (1 H)-one N-heterocycles is …

Although there have been extensive research and progress on the discovery of anticancer
drug over the years, the application of these drugs as stand-alone therapy has been limited …

The constant need for high‐performance aniline‐or phenol‐based fluorophores suitable for
the construction of activity‐based fluorescent probes, led us to study both synthesis and …

We designed a new caging group that can be photoactivated only in the presence of a non-
endogenous enzyme when exposed to 405 nm light. Because cells or tissues can be …

Nanomedicine has seen a significant increase in research on stimuli-responsive activatable
nanoprobes for tumor-specific delivery and diagnosis. The tumor microenvironment has …

Photoactivatable or photoremovable protecting groups (PPGs) have become a powerful
material and gained enormous interest in the field of biomedical applications. PPGs have …