Disease detection with molecular biomarkers: from chemistry of body fluids to nature-inspired chemical sensors
YY Broza, X Zhou, M Yuan, D Qu, Y Zheng… - Chemical …, 2019 - ACS Publications
This article aims to review nature-inspired chemical sensors for enabling fast, relatively
inexpensive, and minimally (or non-) invasive diagnostics and follow-up of the health …
inexpensive, and minimally (or non-) invasive diagnostics and follow-up of the health …
The extended granin family: structure, function, and biomedical implications
A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
Human body fluid proteome analysis
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease
M Puchades, SF Hansson, CL Nilsson… - Molecular brain …, 2003 - Elsevier
By comparing the cerebrospinal fluid (CSF) proteome between Alzheimer's disease (AD)
patients and controls, it may be possible to identify proteins that play a role in the disease …
patients and controls, it may be possible to identify proteins that play a role in the disease …
Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis
Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …
[HTML][HTML] Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
RJ Perrin, R Craig-Schapiro, JP Malone, AR Shah… - PloS one, 2011 - journals.plos.org
Background Ideally, disease modifying therapies for Alzheimer disease (AD) will be applied
during the 'preclinical'stage (pathology present with cognition intact) before severe neuronal …
during the 'preclinical'stage (pathology present with cognition intact) before severe neuronal …
[HTML][HTML] Synaptic proteomics reveal distinct molecular signatures of cognitive change and C9ORF72 repeat expansion in the human ALS cortex
Increasing evidence suggests synaptic dysfunction is a central and possibly triggering factor
in Amyotrophic Lateral Sclerosis (ALS). Despite this, we still know very little about the …
in Amyotrophic Lateral Sclerosis (ALS). Despite this, we still know very little about the …
[HTML][HTML] Proteomics approaches for biomarker and drug target discovery in ALS and FTD
Neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and
frontotemporal dementia (FTD) are increasing in prevalence but lack targeted therapeutics …
frontotemporal dementia (FTD) are increasing in prevalence but lack targeted therapeutics …
Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects
EM Castaño, AE Roher, CL Esh, TA Kokjohn… - Neurological …, 2006 - Taylor & Francis
Objectives: Diagnostic tests able to reveal Alzheimer's disease (AD) in living patients before
cognitive ability is destroyed are urgently needed. Such tests must distinguish AD from other …
cognitive ability is destroyed are urgently needed. Such tests must distinguish AD from other …
Blood and plasma-based proteomic biomarker research in Alzheimer's disease
Alzheimer's disease (AD) is the most important cause of dementia in the elderly. The
molecular alterations preceding this neurodegenerative pathology may take place even 20 …
molecular alterations preceding this neurodegenerative pathology may take place even 20 …