Human monocyte subsets and phenotypes in major chronic inflammatory diseases
Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
Smooth muscle cell fate and plasticity in atherosclerosis
S Allahverdian, C Chaabane, K Boukais… - Cardiovascular …, 2018 - academic.oup.com
Current knowledge suggests that intimal smooth muscle cells (SMCs) in native
atherosclerotic plaque derive mainly from the medial arterial layer. During this process …
atherosclerotic plaque derive mainly from the medial arterial layer. During this process …
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
A Frismantiene, M Philippova, P Erne, TJ Resink - Cellular signalling, 2018 - Elsevier
Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
[HTML][HTML] Macrophages and lipid metabolism
A Remmerie, CL Scott - Cellular immunology, 2018 - Elsevier
Distinct macrophage populations throughout the body display highly heterogeneous
transcriptional and epigenetic programs. Recent research has highlighted that these profiles …
transcriptional and epigenetic programs. Recent research has highlighted that these profiles …
Targeted therapy of atherosclerosis by a broad-spectrum reactive oxygen species scavenging nanoparticle with intrinsic anti-inflammatory activity
Y Wang, L Li, W Zhao, Y Dou, H An, H Tao, X Xu… - ACS …, 2018 - ACS Publications
Atherosclerosis is a leading cause of vascular diseases worldwide. Whereas antioxidative
therapy has been considered promising for the treatment of atherosclerosis in view of a …
therapy has been considered promising for the treatment of atherosclerosis in view of a …
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms
Stable atherosclerotic plaques are characterized by a thick, extracellular matrix-rich fibrous
cap populated by protective ACTA2+ myofibroblast (MF)-like cells, assumed to be almost …
cap populated by protective ACTA2+ myofibroblast (MF)-like cells, assumed to be almost …
[HTML][HTML] Inflammation, oxidative stress and renin angiotensin system in atherosclerosis
K Husain, W Hernandez, RA Ansari… - World journal of …, 2015 - ncbi.nlm.nih.gov
Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Inflammatory cells in atherosclerosis
M Mehu, CA Narasimhulu, DK Singla - Antioxidants, 2022 - mdpi.com
Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …
Cholesterol loading reprograms the microRNA-143/145–myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype
Y Vengrenyuk, H Nishi, X Long, M Ouimet… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—We previously showed that cholesterol loading in vitro converts mouse aortic
vascular smooth muscle cells (VSMC) from a contractile state to one resembling …
vascular smooth muscle cells (VSMC) from a contractile state to one resembling …