Present and future of bronchopulmonary dysplasia

L Bonadies, P Zaramella, A Porzionato… - Journal of clinical …, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …

[HTML][HTML] Pathogenesis of necrotizing enterocolitis: modeling the innate immune response

SM Tanner, TF Berryhill, JL Ellenburg, T Jilling… - The American journal of …, 2015 - Elsevier
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature
infants. The pathophysiology is likely secondary to innate immune responses to intestinal …

Insulin‐like growth factor‐1 signaling in lung development and inflammatory lung diseases

Z Wang, W Li, Q Guo, Y Wang, L Ma… - BioMed research …, 2018 - Wiley Online Library
Insulin‐like growth factor‐1 (IGF‐1) was firstly identified as a hormone that mediates the
biological effects of growth hormone. Accumulating data have indicated the role of IGF‐1 …

rhIGF-1/BP3 preserves lung growth and prevents pulmonary hypertension in experimental bronchopulmonary dysplasia

G Seedorf, C Kim, B Wallace, EW Mandell… - American journal of …, 2020 - atsjournals.org
Rationale: Antenatal factors, such as chorioamnionitis, preeclampsia, and postnatal injury,
are associated with an increased risk for bronchopulmonary dysplasia (BPD) and pulmonary …

Changing expression profiles of mRNA, lncRNA, circRNA, and miRNA in lung tissue reveal the pathophysiological of bronchopulmonary dysplasia (BPD) in mouse …

J Wang, J Yin, X Wang, H Liu, Y Hu… - Journal of cellular …, 2019 - Wiley Online Library
New perinatal care technologies have improved the survival rate of preterm neonates, but
the prevalence of bronchopulmonary dysplasia (BPD), one of the most intractable problems …

The clustering of disorders in infants born before the 28th week of gestation

A Leviton, O Dammann, S Engelke, E Allred… - Acta …, 2010 - Wiley Online Library
Aim: To see whether disorders prevalent in infants born extremely preterm cluster. Design:
Observational cohort study. Setting: University‐affiliated newborn intensive care nurseries …

Hyperoxia stimulates the transdifferentiation of type II alveolar epithelial cells in newborn rats

A Hou, J Fu, H Yang, Y Zhu, Y Pan… - American Journal of …, 2015 - journals.physiology.org
Supplemental oxygen treatment in preterm infants may cause bronchopulmonary dysplasia
(BPD), which is characterized by alveolar simplification and vascular disorganization …

MicroRNA-mRNA interactions in a murine model of hyperoxia-induced bronchopulmonary dysplasia

J Dong, WA Carey, S Abel, C Collura, G Jiang… - BMC genomics, 2012 - Springer
Background Bronchopulmonary dysplasia is a chronic lung disease of premature neonates
characterized by arrested pulmonary alveolar development. There is increasing evidence …

Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation

RS Pais, N Moreno-Barriuso, I Hernández-Porras… - PloS one, 2013 - journals.plos.org
Background Insulin-like Growth Factor 1 (IGF1) is a multifunctional regulator of somatic
growth and development throughout evolution. IGF1 signaling through IGF type 1 receptor …

Differential expression of long non‐coding RNAs in hyperoxia‐induced bronchopulmonary dysplasia

TP Bao, R Wu, HP Cheng, XW Cui… - Cell Biochemistry and …, 2016 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is a common complication of premature birth that
seriously affects the survival rate and quality of life among preterm neonates. Long non …