Background Early predictors for the development of stroke-associated infection may identify
patients at high risk and reduce post-stroke infection and mortality. Methods In 383 …

Acute brain injury and brain death exert detrimental effects on peripheral host cells. Brain-
induced impairment of immune function makes patients more vulnerable to infections that …

Despite considerable research that has contributed to a better understanding of the
pathophysiology of stroke, translation of this knowledge into effective therapies has largely …

Stroke is the second leading cause of death among adults worldwide.(−)-Epigallocatechin-3-
gallate (EGCG) has been demonstrated to exhibit neuroprotective functions in cerebral …

Inflammatory mediators and metalloproteinases are altered in acute ischemic stroke (AIS)
and play a detrimental effect on clinical severity and hemorrhagic transformation of the …

Background: Previous studies indicated that the puerarin injection has been widely
employed in China for the treatment of acute ischemic stroke. We aim to evaluate the …

Cell therapy has been shown as a potential treatment for stroke and other neurological
disorders. Human umbilical cord blood (HUCB) may be a promising source of stem cells for …

Background and aim The neutrophil-to-lymphocyte ratio (NLR) is considered as an
independent and easy-to-measure inflammatory predictor of mortality in patients with acute …

In this issue of Stroke, del Zoppo et al1 report new data on the association between
hyperfibrinogenemia and functional prognosis after ischemic stroke using the placebo data …

Receptor-interacting protein 1 kinase (RIP1K) plays a key role in necroptosis. Necrostatin-1
(Nec-1), a specific inhibitor of RIP1K, provides neuroprotection against ischemic brain injury …