Development of a 18F-Labeled Radiotracer with Improved Brain Kinetics for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Ischemic …

M Fujinaga, R Luo, K Kumata, Y Zhang… - Journal of Medicinal …, 2017 - ACS Publications
We designed four novel acetamidobenzoxazolone compounds 7a–d as candidates for
positron emission tomography (PET) radiotracers for imaging the translocator protein (18 …

Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C] DAC with ultra-high specific activity

J Yui, A Hatori, K Kawamura, K Yanamoto, T Yamasaki… - Neuroimage, 2011 - Elsevier
The aim of this study was to visualize early infarction in the rat brain after ischemia using a
translocator protein (TSPO)(18kDa) PET ligand [11C] DAC with ultra-high specific activity …

Aldosterone synthase gene (CYP11B2) promoter polymorphism as a risk factor for ischaemic stroke in Tunisian Arabs

S Saidi, T Mahjoub, WY Almawi - Journal of the Renin …, 2010 - journals.sagepub.com
Introduction. We investigated the contribution of aldosterone synthase CYP11B2
polymorphism (C—344T) to the age-related changes in blood pressure in stroke patients …

The anti-inflammatory effects of D-allose contribute to attenuation of cerebral ischemia–reperfusion injury

D Gao, N Kawai, T Tamiya - Medical Hypotheses, 2011 - Elsevier
It has been proved that multiple independently lethal mechanisms are involved in cerebral
ischemia–reperfusion injury. Inflammatory processes, mediated by activated leukocytes …

Toward personalized cell therapies: autologous menstrual blood cells for stroke

MCO Rodrigues, LE Glover, N Weinbren… - BioMed Research …, 2011 - Wiley Online Library
Cell therapy has been established as an important field of research with considerable
progress in the last years. At the same time, the progressive aging of the population has …

Body temperature in the acute phase and clinical outcomes after acute ischemic stroke

S Mezuki, R Matsuo, F Irie, Y Shono, T Kuwashiro… - Plos one, 2024 - journals.plos.org
Background This study aimed to examine whether post-stroke early body temperature is
associated with neurological damage in the acute phase and functional outcomes at three …

Recent progress in cell therapy for basal ganglia disorders with emphasis on menstrual blood transplantation in stroke

MCO Rodrigues, J Voltarelli, PR Sanberg… - Neuroscience & …, 2012 - Elsevier
Cerebrovascular diseases are the third leading cause of death and the primary cause of
long-term disability in the United States. The only approved therapy for stroke is tPA, strongly …

Embryonic heat conditioning induces TET-dependent cross-tolerance to hypothalamic inflammation later in life

T Rosenberg, T Kisliouk, T Cramer, D Shinder… - Frontiers in …, 2020 - frontiersin.org
Early life encounters with stress can lead to long-lasting beneficial alterations in the
response to various stressors, known as cross-tolerance. Embryonic heat conditioning …

Activated leukocyte cell adhesion molecule and prognosis in acute ischemic stroke

L Smedbakken, JK Jensen, J Hallén, D Atar, JL Januzzi… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Biomarkers predicting mortality and functional outcome in stroke
may be clinically helpful in identification of patients likely to benefit from intervention …

Measuring serum amyloid a for infection prediction in aneurysmal subarachnoid hemorrhage

L Azurmendi, V Degos, N Tiberti… - Journal of proteome …, 2015 - ACS Publications
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high rates of mortality and
morbidity. Nosocomial infections, such as pneumonia or urinary tract infections, are among …