High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Depression is a common mental disorder in which patients often experience feelings of
sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for …

Exercise is increasingly recommended as a supportive therapy for people with Multiple
Sclerosis (pwMS). While clinical research has still not disclosed the real benefits of exercise …

Major depressive disorder (MDD) has a high prevalence and is a major contributor to the
global burden of disease. This psychiatric disorder results from a complex interaction …

The beneficial effects of exercise on human brain function have been demonstrated in
previous studies. Myokines secreted by muscle have attracted increasing attention because …

We previously reported that physical inactivity (PI) induces cognitive decline and depressive
states, which were ameliorated by regular exercise. However, the mechanism underlying the …

Background Depression is one of the most common mental diseases and the leading cause
of disability worldwide. A dysfunctional gut microbiota-brain axis is one of the main …

Single-factor intervention, such as physical exercise and auditory and visual stimulation,
plays a positive role on the prevention and treatment of Alzheimer's disease (AD); however …

Exercise not only builds up our body but also improves cognitive function. Skeletal muscle
secretes myokine during exercise as a large reservoir of signaling molecules, which can be …

Irisin is involved in various metabolic pathways and is suggested to be a potential agent
capable of preventing onset of Alzheimer's disease (AD) and ameliorating AD …