Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to
acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal …

Microbial communities during winemaking are diverse and change throughout the
fermentation process. Microorganisms not only drive alcohol fermentation, flavor and aroma …

Importance Alcohol consumption rates have been increasing among women in the US,
which may affect mortality rates and sex gaps. Therefore, conducting a comprehensive …

A diagnosis of alcohol use disorder is associated with a higher risk of dementia, but a dose–
response relationship between alcohol intake consumption and cognitive impairment …

Excessive alcohol consumption contributes to a broad clinical spectrum of liver diseases,
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …

Binge drinking (BD) is the most common alcohol consumption model among adolescents.
BD exposure during adolescence disrupts the nervous system function, being involved in …

The half-life of a drug is most commonly defined as the time taken for the plasma or blood
level of the drug to fall by half. Elimination half-life, pharmacologic half-life, and biologic half …

Phosphatidylethanols (PEth) are a group of abnormal phospholipids which are formed
within the human body in the presence of ethanol. As PEth accumulates in red blood cells …

Accurate determination of a person's blood alcohol concentration (BAC) is an important task
in forensic toxicology laboratories because of the existence of statutory limits for driving a …

Heavy drinking and drunkenness, especially in connection with driving, is a global public
health problem. Alcohol (ethanol) is a legal drug, and light‐to‐moderate drinking should not …