MIF and CD74 as Emerging Biomarkers for Immune Checkpoint Blockade Therapy

RM Fey, RA Nichols, TT Tran, AA Vandenbark… - Cancers, 2024 - mdpi.com
Simple Summary While immune checkpoint blockade (ICB) therapy is used successfully to
treat various cancers, many patients develop immune-related adverse side effects (irAEs) …

WISP1 induces the expression of macrophage migration inhibitory factor in human lung fibroblasts through Src kinases and EGFR-activated signaling pathways

ME Christopoulou, SS Skandalis… - … of Physiology-Cell …, 2024 - journals.physiology.org
Wnt1-inducible signaling protein 1 (WISP1/CCN4) is a secreted matricellular protein that is
implicated in lung and airway remodeling. The macrophage migration inhibitory factor (MIF) …

Macrophage migration inhibitory factor may play a protective role in osteoarthritis

M Liu, Z Xie, G Sun, L Chen, D Qi, H Zhang… - Arthritis Research & …, 2021 - Springer
Background Osteoarthritis (OA) is the most prevalent form of arthritis and the major cause of
disability and overall diminution of quality of life in the elderly population. Currently there is …

巨噬细胞迁移抑制因子对干细胞的作用

郑晓晗, 魏艳召, 黄婷, 魏绪芳, 孙圣童, 王埮, 赵振强 - 中国组织工程研究, 2023 - cjter.com
巨噬细胞迁移抑制因子对干细胞的作用 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 27|No.15|May 2023|2395 中国组织工程研究 Chinese Journal of Tissue …

Transcriptional heterogeneity in human diabetic foot wounds

T Sandoval-Schaefer, Q Phan, BC Dash, AJ Prassinos… - Biorxiv, 2023 - biorxiv.org
Wound repair requires the coordination of multiple cell types including immune cells and
tissue resident cells to coordinate healing and return of tissue function. Diabetic foot …

人胚胎干细胞自分泌巨噬细胞迁移抑制因子及受体表达

魏艳召, 郑晓晗, 高仕君, 黄婷, 魏续芳, 陈薪旭… - 中国组织工程研究, 2023 - cjter.com
人胚胎干细胞自分泌巨噬细胞迁移抑制因子及受体表达 Page 1 34|中国组织工程研究|第27卷|第
1期|2023年1月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …

MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study

S Ye, NM Agalave, F Ma, DFD Mahmood… - International Journal of …, 2024 - mdpi.com
Bladder pain is a prominent symptom in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
We studied spinal mechanisms of bladder pain in mice using a model where repeated …

Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities

CN Valdez, GA Sánchez-Zuno, R Bucala… - International Journal of …, 2024 - mdpi.com
Discovered as inflammatory cytokines, MIF and DDT exhibit widespread expression and
have emerged as critical mediators in the response to infection, inflammation, and more …

Single-cell mapping of regenerative and fibrotic healing responses after musculoskeletal injury

RJ Tower, AC Bancroft, AR Chowdary, S Barnes… - Stem cell reports, 2022 - cell.com
After injury, a cascade of events repairs the damaged tissue, including expansion and
differentiation of the progenitor pool and redeposition of matrix. To guide future wound …

Macrophage migration inhibitory factor provides a predictive performance of septic acute kidney injury

T Li, J Zhang, M Long, X Jiang, C Yang, F Wang, L Su… - Shock, 2022 - journals.lww.com
Background: Septic acute kidney injury (AKI) is a common condition in ICU with poor
outcomes. Septic AKI patients have a progressively decreased urine output and increased …