Hypothalamus‐pituitary‐thyroid axis
TM Ortiga‐Carvalho, MI Chiamolera… - Comprehensive …, 2011 - Wiley Online Library
The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
[HTML][HTML] Mechanisms for pituitary tumorigenesis: the plastic pituitary
S Melmed - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
The anterior pituitary gland integrates the repertoire of hormonal signals controlling thyroid,
adrenal, reproductive, and growth functions. The gland responds to complex central and …
adrenal, reproductive, and growth functions. The gland responds to complex central and …
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
N De Roux, E Genin, JC Carel… - Proceedings of the …, 2003 - National Acad Sciences
Hypogonadotropic hypogonadism is defined as a deficiency of the pituitary secretion of
follicle-stimulating hormone and luteinizing hormone, which results in the impairment of …
follicle-stimulating hormone and luteinizing hormone, which results in the impairment of …
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline
ME Molitch, DR Clemmons… - The Journal of …, 2011 - academic.oup.com
Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …
[HTML][HTML] Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans
D Kelberman, K Rizzoti, A Avilion… - The Journal of …, 2006 - Am Soc Clin Investig
The transcription factor SOX2 is expressed most notably in the developing CNS and
placodes, where it plays critical roles in embryogenesis. Heterozygous de novo mutations in …
placodes, where it plays critical roles in embryogenesis. Heterozygous de novo mutations in …
TSH-secreting adenomas
P Beck-Peccoz, L Persani, D Mannavola… - Best Practice & Research …, 2009 - Elsevier
Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism
and account for less than 2% of all pituitary adenomas. In the last years, the diagnosis has …
and account for less than 2% of all pituitary adenomas. In the last years, the diagnosis has …
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline
ME Molitch, DR Clemmons… - The Journal of …, 2006 - academic.oup.com
Objective: The objective is to provide guidelines for the evaluation and treatment of adults
with GH deficiency (GHD). Participants: The chair of the Task Force was selected by the …
with GH deficiency (GHD). Participants: The chair of the Task Force was selected by the …
[HTML][HTML] Over-and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism
KS Woods, M Cundall, J Turton, K Rizotti… - The American Journal of …, 2005 - cell.com
Duplications of Xq26-27 have been implicated in the etiology of X-linked hypopituitarism
associated with mental retardation (MR). Additionally, an expansion of a polyalanine tract …
associated with mental retardation (MR). Additionally, an expansion of a polyalanine tract …
Pituitary cell lines and their endocrine applications
GT Ooi, N Tawadros, RM Escalona - Molecular and cellular endocrinology, 2004 - Elsevier
The pituitary gland is an important component of the endocrine system, and together with the
hypothalamus, exerts considerable influence over the functions of other endocrine glands …
hypothalamus, exerts considerable influence over the functions of other endocrine glands …
Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency
AM Pulichino, S Vallette-Kasic, C Couture… - Genes & …, 2003 - genesdev.cshlp.org
Tpit is a highly cell-restricted transcription factor that is required for expression of the pro-
opiomelanocortin (POMC) gene and for terminal differentiation of the pituitary corticotroph …
opiomelanocortin (POMC) gene and for terminal differentiation of the pituitary corticotroph …