Scope Recent studies have highlighted the vital role of gut microbiota in the pathogenesis of
Alzheimer's disease (AD). However, the effect of the regulation of gut microbiota by dietary …

Trillions of intestinal bacteria in the human body undergo dynamic transformations in
response to physiological and pathological changes. Alterations in their composition and …

Gut bacteria regulate brain pathology of Alzheimer's disease (AD) patients and animal
models; however, the underlying mechanism remains unclear. In this study, 3-month-old …

Background Emerging evidence has shown the potential involvement of phthalates (PAEs)
exposure in the development of dementia with Lewy bodies (DLB). Metabolomics can reflect …

Age and gender have been recognized as two pivotal covariates affecting the composition of
the gut microbiota. However, their mediated variations in microbiota seem to be inconsistent …

Alzheimer's disease (AD) is a memory-related disease that occurs in the human brain where
neurons become degenerative. It is an evolved form of dementia that deteriorates over time …

HIV-associated neurocognitive disorder (HAND) has become a chronic neurodegenerative
disease affecting the quality of life in people living with HIV (PLWH). Despite an established …

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder and a leading cause of
dementia. Aging is a significant risk factor for AD, emphasizing the importance of early …

Gut microorganisms have been shown to significantly impact on central function and studies
that have associated brain disorders with specific bacterial genera have advocated an …

Importance Research is beginning to elucidate the sophisticated mechanisms underlying
the microbiota-gut-brain-immune interface, moving from primarily animal models to human …