Alzheimer disease (AD) is the most common contributor to dementia in the world, but
strategies that slow or prevent its clinical progression have largely remained elusive, until …

The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Background Previous studies show that antibiotic-mediated (abx) alteration of the gut
microbiome (GMB) results in a reduction of amyloid beta (Aβ) plaques and proinflammatory …

In humans, the gut microbiota (GM) are known to play a significant role in the metabolism of
nutrients and drugs, immunomodulation, and pathogen defense by inhabiting the …

The advent of highthroughput 'omics' technologies has improved our knowledge of gut
microbiome in human health and disease, including Alzheimer's disease (AD), a …

Spouses of Alzheimer's disease (AD) patients are at a higher risk of developing incidental
dementia. However, the causes and underlying mechanism of this clinical observation …

The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …

The role of neurotrophic factors, oxidative stress, and inflammation in the pathogenesis of
Alzheimer's disease (AD) has been explored. Animal studies have reported the positive …

Aging is a complex process influenced by genetics and the environment, leading to
physiological decline and increased susceptibility to diseases. Cognitive decline is a …