Current state and novel outlook on prevention and treatment of rising antibiotic resistance in urinary tract infections

EK Sher, A Džidić-Krivić, A Sesar, EK Farhat… - Pharmacology & …, 2024 - Elsevier
Antibiotic-resistant bacteria are currently an important public health concern posing a
serious threat due to their resistance to the current arsenal of antibiotics. Uropathogens …

Antimicrobial and antibiofilm activities of chromone derivatives against uropathogenic Escherichia coli

BR Boya, JH Lee, J Lee - Microbiological Research, 2024 - Elsevier
Uropathogenic Escherichia coli (UPEC) is a urinary tract pathogen responsible for most
nosocomial urinary tract infections and can cause severe conditions like acute cystitis of the …

A review of the mechanisms that confer antibiotic resistance in pathotypes of E. coli

S Nasrollahian, JP Graham, M Halaji - Frontiers in Cellular and …, 2024 - frontiersin.org
The dissemination of antibiotic resistance in Escherichia coli poses a significant threat to
public health worldwide. This review provides a comprehensive update on the diverse …

Incidence of drug-resistant hospital-associated Gram-negative bacterial infections, the accompanying risk factors, and clinical outcomes with treatment

L Badger-Emeka, AS Al Rashed, RY Aljindan… - Antibiotics, 2023 - mdpi.com
Extensive drug resistance to bacterial infections in hospitalised patients is accompanied by
high morbidity and mortality rates due to limited treatment options. This study investigated …

Correlation between antimicrobial resistance, biofilm formation, and virulence determinants in uropathogenic Escherichia coli from Egyptian hospital

SA Alshaikh, T El-Banna, F Sonbol… - Annals of Clinical …, 2024 - Springer
Abstract Background Uropathogenic Escherichia coli (UPEC) is the main etiological agent
behind community-acquired and hospital-acquired urinary tract infections (UTIs), which are …

Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models

K Rox, R Jansen, T Lukežič… - Microbiology …, 2024 - Am Soc Microbiol
The quest for novel anti-infectives against drug-resistant pathogens of the so-called
ESKAPE panel is accompanied by intensive research aiming to find treatment options for the …

A broad-spectrum antibacterial hydrogel based on the synergistic action of Fmoc–phenylalanine and Fmoc–lysine in a co-assembled state

BD Gupta, A Halder, T Vijayakanth, N Ghosh… - Journal of Materials …, 2024 - pubs.rsc.org
Multicomponent biomolecular self-assembly is fundamental for accomplishing complex
functionalities of biosystems. Self-assembling peptides, amino acids, and their conjugates …

Comparison of Chinese medicine additives for antibiotic resistance risks in the Wuding chickens under high stocking density: Advantages and drawbacks

H Hu, Y Huang, C Shi, A Li, Q Mi, K Wang… - Journal of Cleaner …, 2024 - Elsevier
Abstract Traditional Chinese medicines (TCMs) with anti-pathogenic properties have been
increasingly utilized in animal husbandry as substitutes for antibiotics. However, lingering …

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

P Dulyayangkul, T Beavis, WWY Lee, R Ardagh… - PLoS …, 2024 - journals.plos.org
Amikacin and piperacillin/tazobactam are frequent antibiotic choices to treat bloodstream
infection, which is commonly fatal and most often caused by bacteria from the family …

In silico-designed antimicrobial peptide targeting MRSA and E. coli with antibacterial and antibiofilm actions

H Madni, HA Mohamed, HAM Abdelrahman… - Scientific Reports, 2024 - nature.com
Antibiotic resistance is a paramount global health issue, with numerous bacterial strains
continually fortifying their resistance against diverse antibiotics. This surge in resistance …