Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Alzheimer's disease is a neurodegenerative disorder that causes age-dependent
neurological and cognitive declines. The treatments for Alzheimer's disease pose a …

Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several
physiological and pathological states, including Alzheimer's disease (AD). With a prominent …

Protein corona presents a major obstacle to bench-to-bedside translation of targeted drug
delivery systems, severely affecting targeting yields and directing unfavorable …

The pathological processes leading to synapse loss, neuronal loss, brain atrophy and
gliosis in Alzheimer's disease (AD) and their relation to vascular disease and immunological …

Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …

Abstract Trimethylamine-N-oxide (TMAO), a metabolite of gut microbiota, has been
implicated in the pathogenesis of Alzheimer's disease (AD). However, the mechanisms by …

Several lines of epidemiological evidence link increased levels of high-density lipoprotein-
cholesterol (HDL-C) with lower risk of Alzheimer's disease (AD). This observed relationship …

Much evidence suggests a protective role of high-density lipoprotein (HDL) and its major
apolipoprotein apoA-I, in Alzheimer's disease (AD). The biogenesis of nascent HDL derived …