Use of genetically modified lactic acid bacteria and bifidobacteria as live delivery vectors for human and animal health

R Levit, NG Cortes-Perez, A de Moreno de Leblanc… - Gut …, 2022 - Taylor & Francis
There is now strong evidence to support the interest in using lactic acid bacteria (LAB) in
particular, strains of lactococci and lactobacilli, as well as bifidobacteria, for the development …

[HTML][HTML] Recent advances in the therapeutic efficacy of artesunate

N Ruwizhi, RB Maseko, BA Aderibigbe - Pharmaceutics, 2022 - mdpi.com
Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line
drug for treating malaria. Apart from treating malaria, artesunate has also been found to …

[HTML][HTML] Malaria detection using advanced deep learning architecture

W Siłka, M Wieczorek, J Siłka, M Woźniak - Sensors, 2023 - mdpi.com
Malaria is a life-threatening disease caused by parasites that are transmitted to humans
through the bites of infected mosquitoes. The early diagnosis and treatment of malaria are …

[HTML][HTML] Impact of the COVID-19 pandemic on malaria control in Africa: A preliminary analysis

L Gao, Q Shi, Z Liu, Z Li, X Dong - Tropical Medicine and Infectious …, 2023 - mdpi.com
Malaria remains a significant public health concern in Africa, and the emerging coronavirus
disease 2019 (COVID-19) pandemic may have negatively impacted malaria control. Here …

[HTML][HTML] Analysis of fifty years of severe malaria worldwide research

JA Garrido-Cardenas, L González-Cerón… - Pathogens, 2023 - mdpi.com
This study analyzed fifty years of severe malaria research worldwide. Malaria is a parasitic
disease that continues to have a significant impact on global health, particularly in sub …

[HTML][HTML] Identification of novel Plasmodium falciparum dihydroorotate dehydrogenase inhibitors for malaria using in silico studies

AA Alzain, ZAM Ahmed, MA Mahadi, FA Elbadwi - Scientific African, 2022 - Elsevier
Malaria, that ancient infectious disease is considered a great health problem due to its
highly infectious and mortality rates. The more harmful kind of malaria is Plasmodium …

[HTML][HTML] Antiparasitic effects of sulfated polysaccharides from marine hydrobionts

NN Besednova, TS Zaporozhets, BG Andryukov… - Marine Drugs, 2021 - mdpi.com
This review presents materials characterizing sulfated polysaccharides (SPS) of marine
hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of …

Dual quinoline-hybrid compounds with antimalarial activity against Plasmodium falciparum parasites

GJ da Silva Neto, LR Silva, RJM de Omena… - New Journal of …, 2022 - pubs.rsc.org
Although we have at our disposal relatively low-cost drugs that can be prescribed for the
treatment of malaria, the prevalence of resistant strains of the causative parasite has …

[HTML][HTML] Estimation of pediatric dosage of antimalarial drugs, using pharmacokinetic and physiological approach

EKG Mhango, BS Snorradottir, BHK Kachingwe… - Pharmaceutics, 2023 - mdpi.com
Most of the individuals who die of malaria in sub–Saharan Africa are children. It is, therefore,
important for this age group to have access to the right treatment and correct dose …

[HTML][HTML] Trained immunity: a cutting edge approach for designing novel vaccines against parasitic diseases?

J Zhu, J Liu, C Yan, D Wang, W Pan - Frontiers in Immunology, 2023 - frontiersin.org
The preventive situation of parasitosis, a global public health burden especially for
developing countries, is not looking that good. Similar to other infections, vaccines would be …